垂体结核瘤:一种非常罕见部位的常见病理

S. Balaji, K. Selvamuthukumaran
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引用次数: 0

摘要

垂体结核瘤极为罕见,即使在结核病流行的发展中国家,文献中报告的病例总数也不到100例。误诊为垂体腺瘤是常见的,晚期诊断可导致永久性内分泌功能障碍和/或长期的神经系统后遗症。垂体结核瘤和模拟腺瘤是非常罕见的。我们报告了一例以严重头痛为表现的鞍上肿块患者的小病例系列,所有这些患者以前没有任何结核病史,并且放射学和微生物学证据表明身体其他部位有结核病。所有患者均行内镜下经蝶窦切除肿物,组织病理检查提示垂体结核瘤。开始并持续了一年的抗结核治疗,所有三名患者在一年后都很好地控制了疾病,激素水平正常,尽管所有三名患者在手术后最初三个月都需要小剂量的类固醇(强的松龙5mg)。
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Pitutary tuberculoma: A verycommon pathology in a very uncommon location
Pituitary Tuberculoma is extremely rare, even in developing countries where tuberculosis is endemic with total reported cases in the literature fewer than a hundred. Misdiagnosis as pituitary adenoma is common and late diagnosis can result in a permanent endocrine dysfunction and/or long-term neurologic sequela. Pituitary Tuberculoma, and mimicking adenomas are very unusual. We report a small case series of a patient with sellar/ suprasellar mass, who presented with severe headache, all these patients didn’t have any previous history of tuberculosis and radiological and microbiological evidence of Tuberculosis elsewhere in the body. All these patients underwent endoscopic transsphenoidal resection of the mass and histo pathological examination was suggestive of pituitary Tuberculoma. Antituberculous therapy was started and continued for one year, all three patients had good control of the disease and hormonal profile was normal at the end of one year, though all three patients required a small dose of steroid (Prednisolone 5mg) for the initial three months after surgery.
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