改进环形比法用于疟疾治疗后诊断的恶性疟原虫自动检测系统

S. Kareem, I. Kale, R. Morling
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引用次数: 22

摘要

疟疾寄生虫恶性疟原虫的配子体对抗疟药物具有高度耐药性。即使在成功治疗疟疾后,也可以检测到血液中存在的疟原虫。本文介绍了一种改进的环形比方法,该方法成功地在血薄膜图像中定位和区分了恶性疟原虫的配子体。该方法可作为疟疾治疗后配子细胞检测的有效工具。它还可以识别图像中存在的任何白细胞(wbc),并丢弃其他伪影和非感染细胞。它利用基于细胞的结构、颜色和几何形状的信息,不需要通常用于细胞检测的任何分割或非照明校正技术。
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Automated P.falciparum Detection System for Post-Treatment Malaria Diagnosis Using Modified Annular Ring Ratio Method
The gametocytes of the malaria parasite Plasmodium falciparum are highly resistant to antimalarial drugs. Its presence in the blood can be detected even after a successful malaria treatment. This paper explains a modified Annular Ring Ratio method which successfully locates and differentiates gametocytes of P. falciparum species in thin blood film images. The method can be used as an efficient tool for gametocyte detection for post-treatment malaria diagnosis. It also identifies the presence of any White Blood Cells (WBCs) in the image, and discards other artifacts and non infected cells. It utilizes the information based on structure, color and geometry of the cells and does not require any segmentation or non-illumination correction techniques that are commonly used for cell detection.
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