Probiotic and Prebiotic Interventions for Obesity and Diabetes

Diabetes and obesity are two trending metabolic disorder which leads to major complications in all cases despite of age. Both are strictly correlated and hence called diabesity. Diet is the major factor which contributes to diabesity. The microbial diversity and number in the gut environment mainly depends on the food consumed in healthy individuals. The microflora in gut profoundly affects the host metabolism through several mechanisms. There is a significant difference between the microfloral composition in diabetic and nondiabetic people as well as obese and non-obese. High fat/carbohydrate diet always promotes the establishment of putrefying and opportunistic pathogens. Supplementation of probiotics and prebiotics is a good practice to maintain a healthier gut thereby improving the host functions. The review mainly discuss about the beneficial effects of gut flora/probiotics along with prebiotics in T1D, T2D and obesity.