对照试验中皮肤与土壤接触的调查

J. Kissel, J. Shirai, K. Y. Richter, R. Fenske
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引用次数: 42

摘要

华盛顿大学进行了一系列实验室、温室和田间实验,以改进皮肤/土壤途径风险计算的经验基础。本文介绍了在温室中进行的对照试验的结果,在温室中,志愿者在用荧光标记剂修饰的土壤中从事活动。活动包括种植植物和铺设管道,由成人和儿童玩耍。手、前臂、小腿和面部的土壤接触使用荧光测量和重量测量进行检查。结果提供了有关活动前和活动后负荷、与选定活动相关的接触程度以及服装、活动持续时间和土壤湿度的影响的信息。活动前负荷与先前报道的观察结果一致。活动结束后,除手部外,皮肤覆盖基本上不完整。因此,当地的土壤负荷可能明显偏离w。
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Investigation of Dermal Contact with Soil in Controlled Trials
A series of laboratory, greenhouse, and field experiments have been conducted at the University of Washington to improve the empirical grounding of dermal/soil pathway risk calculations. This article presents results from controlled trials, conducted in a greenhouse, in which volunteers engaged in activities in soil amended with a fluorescent marker. Activities included transplanting of bedding plants and laying of pipe by adults and children's play. Soil contact on hands, forearms, lower legs, and faces was examined using both fluoro-metric and gravimetric measurements. Results provide information on pre- and postactivity loadings, the extent of contact associated with the selected activities, and the effects of clothing, activity duration, and soil moisture. Preactivity loadings were consistent with previously reported observations. Following activity, skin coverage was found to be substantially incomplete except on hands. Local soil loadings may therefore deviate markedly from mean values obtained by w...
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