幽门螺旋弯曲杆菌(C. pylori):消化性和炎性胃十二指肠病理中的偶然发现还是恒定的致病因素?个人观察)。

A Licata, P Naso, G Bartoloni, G Bonanno, G Di Gaetano, N Torcetta
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引用次数: 0

摘要

胃窦粘膜中CP的检测导致了这种细菌在消化性溃疡和/或炎症性胃十二指肠疾病的发病和持续中潜在的致病作用的假设。在回顾文献后,作者报告了110例有症状的胃窦粘膜中C.P.的发生率。内镜检查显示阴性诊断,或存在胃和/或十二指肠溃疡,或特异性炎症性疾病。采用快速尿素试验和改良吉姆萨染色对内镜活检标本进行组织形态学分析。86.6%的十二指肠溃疡、94.8%的胃-十二指肠炎症和29.4%的内镜下正常患者存在C.P.。这些结果证实,cp不应被视为偶然发现,而应被视为几乎是一个恒定的因素。强调在内窥镜检查期间进行快速尿素试验的重要性,因为如果呈阳性,可以尽快开始适当的治疗方案。
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[Campylobacter pylori (C. pylori): an occasional finding or a constant pathogenetic factor in peptic and inflammatory gastroduodenal pathology? Personal observations].

The detection of CP in the mucosa of the gastric antrum had led to the supposition of this bacterium's potential pathogenetic role in the onset and continuation of peptic ulcer and/or inflammatory gastroduodenal disease. After reviewing the literature, the Authors report the incidence rate of the presence of C.P. in the mucosa of the gastric antrum in 110 symptomatic patients. Endoscopic examination revealed a negative diagnosis, or the presence of gastric and/or duodenal ulcer, or aspecific inflammatory disease. C.P. was detected using the quick urea test and histomorphological analysis after modified Giemsa staining on bioptic endoscopic specimens. C.P. were present in 86.6% of duodenal ulcers, 94.8% of gastro-duodenal inflammation, and 29.4% of endoscopical normal patients. These results confirm that C.P. should not be considered an occasional finding but almost a constant factors. The importance of performing the quick urea test during endoscopic examination is underlined, since if positive an appropriate therapeutic protocol can be started as soon as possible.

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