维尔纳综合征。

IF 0.5 Q4 DERMATOLOGY Przeglad dermatologiczny Pub Date : 1990-11-01
T Kołodziej, J Maj, M Ziarkiewicz
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引用次数: 0

摘要

本文描述了一例典型的维尔纳氏综合征。所有的特征都存在,即:肌肉和皮下组织萎缩,尤其是肢体远端部位,毛发减少和灰白,受压部位(肘部、足部)出现大量萎缩性溃疡和角化过度病变,所有骨骼弥漫性骨质疏松症,以手和足部最为严重,活动性龋齿,双侧白内障,声带萎缩引起的高音、马音,内分泌紊乱,尤其是睾酮、促卵泡激素和催乳素,外生殖器发育不全,血糖曲线异常。强调了维尔纳综合征与生理衰老的深远相似之处。对合成代谢药物反应良好。
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[Werner's Syndrome].

A typical case of Werner's syndrome was described. All characteristic features were present i.e.: atrophy of muscle and subcutaneous tissue, especially in distal parts of limbs, reduced and gray hairs, numerous atrophic ulcers and hyperkeratotic lesions in points under the pressure (elbow, feet), diffused osteoporosis in all bones, the most intensive in hands and feet, activity dental caries, bilateral cataract, high pitched, horse voice, caused by atrophy of voice cords, endocrinologic disturbances especially concerning testosterone, follicle stimulating hormone, and prolactin, hypoplasia of external genitals, the abnormal blood glucose curve. Far reaching resemblance of the Werner's syndrome to the physiological senility was emphasized. Good reaction to anabolic drugs was described.

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来源期刊
CiteScore
0.80
自引率
14.30%
发文量
9
审稿时长
12 weeks
期刊介绍: Przegląd Dermatologiczny (ang. Dermatological Review) is a bimonthly magazine of the Polish Dermatological Association. It publishes original (clinical and experimental) papers, review papers, care reports, reports from congresses, reviews of books, announcements, letters to the editor and special papers (requested by the editors), concerning selected dermatological and interdisciplinary issues. Papers sent to the editor are reviewed.
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