COVID-19感染的血液学特征

D. S.
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引用次数: 0

摘要

在COVID-19中,短暂和可逆的骨髓生成和颗粒生成紊乱。外周血涂片的特征性变化有助于诊断、预后和治疗方案。淋巴细胞计数减少,中性粒细胞比(NLR)升高是明显的异常。冠状病毒主要影响肺部,因为大多数ACE-2受体存在于肺部。冠状细胞有S型尖峰,这有助于将其附着在ACE -2受体上,主要影响II型肺细胞,导致毛细血管渗漏和肺泡水肿,导致呼吸困难。COVID-19是一场全球大流行,由于疾病在发生之前是一个未知的实体,因此需要对预测、治疗和诊断方案进行更多的研究。
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Haematological Profile in COVID-19 Infection
In COVID-19 transitory and reversible perturbation of myelopoeisis and granulopoiesis is disordered. Characteristic changes on peripheral blood smear can help in diagnosis, may be in prognosis and treatment protocols. Decrease in lymphocyte count and increase in the neutrophilic lymphocytic ratio (NLR ratio) are the obvious abnormalities detected. Coronovirus mainly affects lungs as most of the ACE-2 receptors are present in lung. Corona has S spikes which helps in attaching it to the ACE -2 Receptor mainly affecting the type II pneumocytes causing capillary leakage and alveolar edema leading to breathing difficulty. COVID-19 is a global pandemic more research is required for prognostication, treatment and diagnostic protocols as disease was an unknown entity before its occurrence.
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