[一项激励工作场所粪便潜血检测的随机对照试验]。

C Y Lee
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引用次数: 0

摘要

在美国,结直肠癌是仅次于肺癌的第二大癌症死亡原因。研究表明,粪便潜血(FOB)试验对早期发现结直肠癌是有效的。为了激励工作场所FOB测试,进行了一项随机对照试验。来自华盛顿州三个联邦机构的40岁及以上的雇员被随机分为对照组(n = 139)和干预组(n = 139),对照组收到一封说明在工作场所诊所可以进行FOB测试的信,干预组收到关于结直肠癌事实和结直肠癌风险评估的信。结直肠癌风险评估包括一个人患结直肠癌的风险与他/她的同龄人相比的“正常”,“中等”或“高”风险状态的反馈。3个月后,向所有参与者发送随访问卷,以衡量干预的有效性。在三个主要结局的分析中,通过logistic回归控制两个可能的混杂因素(饮食脂肪和结直肠癌家族史)。根据对工作场所临床记录的回顾,干预组在随访期间对FOB测试的依从率比对照组高4.3% (p = .10)。干预对员工未来一年内接受FOB测试的意向影响最大(干预组62.6%,对照组36.2%,OR = 3.18, p < 0.001)。(摘要删节250字)
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[A randomized controlled trial to motivate worksite fecal occult blood testing].

Colorectal cancer is second only to lung cancer as a cause of death due to cancer in the United States. Studies have shown that fecal occult blood (FOB) tests are effective in detecting colorectal cancer in its early stages. To motivate worksite FOB testing, a randomized controlled trial was conducted. Employees 40 years or older from three federal agencies in Washington State were randomized to a control group (n = 139) which received a letter stating the availability of the FOB test at the worksite clinic or to an intervention group (n = 139) which received the letter about facts on colorectal cancer and a Colorectal Cancer Risk Appraisal. The Colorectal Cancer Risk Appraisal included a feedback on an individual's risk of developing colorectal cancer compared to his/her peers in terms of 'normal', 'moderate', or 'high' risk status. After 3 months, a follow-up questionnaire was sent to all participants to measure the effectiveness of the intervention. In the analysis of the three major outcomes, two possible confounding factors (dietary fat and family history of colorectal cancer) were controlled by logistic regression. Based on a review of the worksite clinic records, the intervention group had 4.3% higher compliance rate with the FOB test during the follow-up period compared to the control group (p = .10). The largest effect of the intervention was on the employees' intention to get a FOB test within the next year (62.6% in the intervention group vs. 36.2% in the control group, OR = 3.18, p less than .001).(ABSTRACT TRUNCATED AT 250 WORDS)

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