维生素d预防骨质疏松性骨折。

JIMÉNEZ-OLIVARES, LAJARA MARCO, González-Navarro, MAHIQUES-SEGURA, MARTÍN-GRANDES, MARTÍNEZ-MÉNDEZ
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摘要

简介:本研究的目的是展示口服维生素d和钙补充剂计划在髋部骨折患者中预防骨质疏松性骨折的初步结果。方法:对65岁以上髋部骨折患者进行前瞻性比较队列研究。根据入院时血清维生素d水平将患者分为两组:1)低维生素d组,58例患者出院时口服维生素d加钙;2)对照组,13例维生素d水平正常的患者没有补充维生素d。结果:由于缺乏正常维生素d水平的患者,样本量无法完成。低维d组术后2年骨折发生率为20.7%,对照组为15.4%,差异无统计学意义(p = 0.664)。结论:目前,根据现有数据,口服维生素d和钙补充剂在预防随后的髋部骨折方面没有显示出有效性。
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La vitamina-D para la prevención de fracturas osteoporóticas.
Introduction: The objective of this study was to show the initial results of an oral vitamin-D and calcium supplementation program in patients who had suffered a hip fracture for the prevention of subsequent fractures considered osteoporotic. Method: Prospective comparative cohorts study in patients older than 65 operated for hip fracture. The patients were divided into two groups according to the serum level of vitamin-D at admission: 1) hypovit-D group, 58 patients who were prescribed oral vitamin-D and calcium at discharge; 2) control group, 13 patients with a normal level of vitamin-D who did not have that supplementation. Results: The sample size could not be completed due to the scarcity of patients with normal vitamin-D levels. The subsequent fracture rate in the following two years was 20.7% in the hypovit-D group and 15.4% in control group, with no significant difference (p = 0.664). Conclusion: provisionally, with the available data, oral vitamin-D and calcium supplementation have not shown effectiveness in preventing a subsequent hip fracture.
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