两点Dixon和六点Dixon磁共振技术在肝脂肪变性的检测、定量和分级中的应用。

IF 1.4 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING World journal of radiology Pub Date : 2023-10-28 DOI:10.4329/wjr.v15.i10.293
Mohamed Elfaal, Alanna Supersad, Craig Ferguson, Stephanie Locas, Florin Manolea, Mitchell P Wilson, Medica Sam, Wendy Tu, Gavin Low
{"title":"两点Dixon和六点Dixon磁共振技术在肝脂肪变性的检测、定量和分级中的应用。","authors":"Mohamed Elfaal, Alanna Supersad, Craig Ferguson, Stephanie Locas, Florin Manolea, Mitchell P Wilson, Medica Sam, Wendy Tu, Gavin Low","doi":"10.4329/wjr.v15.i10.293","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Hepatic steatosis is a very common problem worldwide.</p><p><strong>Aim: </strong>To assess the performance of two- and six-point Dixon magnetic resonance (MR) techniques in the detection, quantification and grading of hepatic steatosis.</p><p><strong>Methods: </strong>A single-center retrospective study was performed in 62 patients with suspected parenchymal liver disease. MR sequences included two-point Dixon, six-point Dixon, MR spectroscopy (MRS) and MR elastography. Fat fraction (FF) estimates on the Dixon techniques were compared to the MRS-proton density FF (PDFF). Statistical tests used included Pearson's correlation and receiver operating characteristic.</p><p><strong>Results: </strong>FF estimates on the Dixon techniques showed excellent correlation (≥ 0.95) with MRS-PDFF, and excellent accuracy [area under the receiver operating characteristic (AUROC) ≥ 0.95] in: (1) Detecting steatosis; and (2) Grading severe steatosis, (<i>P</i> < 0.001). In iron overload, two-point Dixon was not evaluable due to confounding T2* effects. FF estimates on six-point Dixon <i>vs</i> MRS-PDFF showed a moderate correlation (0.82) in iron overload <i>vs</i> an excellent correlation (0.97) without iron overload, (<i>P</i> < 0.03). The accuracy of six-point Dixon in grading mild steatosis improved (AUROC: 0.59 to 0.99) when iron overload cases were excluded. The excellent correlation (> 0.9) between the Dixon techniques <i>vs</i> MRS-PDFF did not change in the presence of liver fibrosis (<i>P</i> < 0.01).</p><p><strong>Conclusion: </strong>Dixon techniques performed satisfactorily for the evaluation of hepatic steatosis but with exceptions.</p>","PeriodicalId":23819,"journal":{"name":"World journal of radiology","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2023-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631370/pdf/","citationCount":"0","resultStr":"{\"title\":\"Two-point Dixon and six-point Dixon magnetic resonance techniques in the detection, quantification and grading of hepatic steatosis.\",\"authors\":\"Mohamed Elfaal, Alanna Supersad, Craig Ferguson, Stephanie Locas, Florin Manolea, Mitchell P Wilson, Medica Sam, Wendy Tu, Gavin Low\",\"doi\":\"10.4329/wjr.v15.i10.293\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Hepatic steatosis is a very common problem worldwide.</p><p><strong>Aim: </strong>To assess the performance of two- and six-point Dixon magnetic resonance (MR) techniques in the detection, quantification and grading of hepatic steatosis.</p><p><strong>Methods: </strong>A single-center retrospective study was performed in 62 patients with suspected parenchymal liver disease. MR sequences included two-point Dixon, six-point Dixon, MR spectroscopy (MRS) and MR elastography. Fat fraction (FF) estimates on the Dixon techniques were compared to the MRS-proton density FF (PDFF). Statistical tests used included Pearson's correlation and receiver operating characteristic.</p><p><strong>Results: </strong>FF estimates on the Dixon techniques showed excellent correlation (≥ 0.95) with MRS-PDFF, and excellent accuracy [area under the receiver operating characteristic (AUROC) ≥ 0.95] in: (1) Detecting steatosis; and (2) Grading severe steatosis, (<i>P</i> < 0.001). In iron overload, two-point Dixon was not evaluable due to confounding T2* effects. FF estimates on six-point Dixon <i>vs</i> MRS-PDFF showed a moderate correlation (0.82) in iron overload <i>vs</i> an excellent correlation (0.97) without iron overload, (<i>P</i> < 0.03). The accuracy of six-point Dixon in grading mild steatosis improved (AUROC: 0.59 to 0.99) when iron overload cases were excluded. The excellent correlation (> 0.9) between the Dixon techniques <i>vs</i> MRS-PDFF did not change in the presence of liver fibrosis (<i>P</i> < 0.01).</p><p><strong>Conclusion: </strong>Dixon techniques performed satisfactorily for the evaluation of hepatic steatosis but with exceptions.</p>\",\"PeriodicalId\":23819,\"journal\":{\"name\":\"World journal of radiology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2023-10-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631370/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"World journal of radiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4329/wjr.v15.i10.293\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"World journal of radiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4329/wjr.v15.i10.293","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0

摘要

背景:肝脂肪变性是世界范围内非常普遍的问题。目的:评价二点和六点迪克森磁共振(MR)技术在肝脂肪变性的检测、定量和分级中的应用价值。方法:对62例疑似实质性肝病患者进行单中心回顾性研究。MR序列包括两点Dixon、六点Dixon、MR光谱(MRS)和MR弹性成像。将Dixon技术估计的脂肪分数(FF)与mrs质子密度FF (PDFF)进行比较。使用的统计检验包括皮尔逊相关和接受者工作特征。结果:Dixon技术的FF估计值与MRS-PDFF具有良好的相关性(≥0.95),并且在以下方面具有良好的准确性[受试者工作特征下面积(AUROC)≥0.95]:(1)检测脂肪变性;(2)重度脂肪变性分级(P < 0.001)。在铁超载时,由于混淆T2*效应,两点Dixon不能评估。6点Dixon与MRS-PDFF的FF估计显示,铁超载的中度相关性(0.82)与无铁超载的极好相关性(0.97)(P < 0.03)。当排除铁超载病例时,6点Dixon分级轻度脂肪变性的准确性提高(AUROC: 0.59至0.99)。Dixon技术与MRS-PDFF之间的极好相关性(> 0.9)在肝纤维化存在时没有改变(P < 0.01)。结论:Dixon技术对肝脂肪变性的评价令人满意,但也有例外。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Two-point Dixon and six-point Dixon magnetic resonance techniques in the detection, quantification and grading of hepatic steatosis.

Background: Hepatic steatosis is a very common problem worldwide.

Aim: To assess the performance of two- and six-point Dixon magnetic resonance (MR) techniques in the detection, quantification and grading of hepatic steatosis.

Methods: A single-center retrospective study was performed in 62 patients with suspected parenchymal liver disease. MR sequences included two-point Dixon, six-point Dixon, MR spectroscopy (MRS) and MR elastography. Fat fraction (FF) estimates on the Dixon techniques were compared to the MRS-proton density FF (PDFF). Statistical tests used included Pearson's correlation and receiver operating characteristic.

Results: FF estimates on the Dixon techniques showed excellent correlation (≥ 0.95) with MRS-PDFF, and excellent accuracy [area under the receiver operating characteristic (AUROC) ≥ 0.95] in: (1) Detecting steatosis; and (2) Grading severe steatosis, (P < 0.001). In iron overload, two-point Dixon was not evaluable due to confounding T2* effects. FF estimates on six-point Dixon vs MRS-PDFF showed a moderate correlation (0.82) in iron overload vs an excellent correlation (0.97) without iron overload, (P < 0.03). The accuracy of six-point Dixon in grading mild steatosis improved (AUROC: 0.59 to 0.99) when iron overload cases were excluded. The excellent correlation (> 0.9) between the Dixon techniques vs MRS-PDFF did not change in the presence of liver fibrosis (P < 0.01).

Conclusion: Dixon techniques performed satisfactorily for the evaluation of hepatic steatosis but with exceptions.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
World journal of radiology
World journal of radiology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
自引率
8.00%
发文量
35
期刊最新文献
Asymmetric outcomes in bilateral maxillary impacted tooth extractions: A case report. Breast cancer imaging-clinical experience with two-dimensional-shear wave elastography: A retrospective study. Cryoablation for intrapulmonary bronchial cyst: A case report. Cystic ductal adenocarcinoma of pancreas complicated with neuroendocrine tumor: A case report and review of literature. Ectopic recurrence following treatment of arteriovenous malformations in an adult: A case report and review of literature.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1