荟萃分析:乳前喂养和补充维生素A对6-59月龄儿童发育迟缓的影响

Aulia Alifariani, Bhisma Murti, Rita Benya Adriani
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引用次数: 0

摘要

背景:发育迟缓是指五岁以下儿童(学步儿童)由于慢性营养不良和反复感染而无法茁壮成长的状况,特别是在生命最初的1000天内,这是一个营养充足的黄金时期。本研究旨在通过荟萃分析研究乳前喂养和维生素A对6-59月龄儿童发育迟缓发生率的影响。对象和方法:采用PRISMA流程图和PICO模型进行meta分析。人群:6-59个月的儿童。干预:给予泌乳前喂养和维生素a比较:不给予泌乳前喂养和维生素a结局:发育迟缓。使用的在线数据库是Google Scholar、ProQuest和Elsevier,关键词是“发育迟缓”、“泌乳前喂养”、“维生素A”、“6-59个月的儿童”、“多元”和“横断面”。2013-2023年发表的15项横断面研究符合纳入标准。采用RevMan 5.3软件进行分析。结果:对来自埃塞俄比亚、乌干达、索马里、印度尼西亚和苏丹6-59月龄儿童的15篇采用横断面研究设计的文章进行荟萃分析,共纳入94,212名研究对象。荟萃分析的结果显示,在6-59个月的儿童中,不给予泌乳前喂养对降低发育迟缓的风险有影响。未给予泌乳前喂养的儿童发育迟缓的风险是给予泌乳前喂养的儿童的0.57倍(aOR= 0.57;95% CI= 0.38 ~ 0.84;p= 0.005),未服用维生素A的儿童发育迟缓的风险是服用维生素A的儿童的1.19倍(aOR= 1.19;95% CI= 1.00 ~ 1.41;p = 0.050)。结论:未给予乳前喂养和给予维生素A的儿童可降低6-59月龄儿童发育迟缓的风险。关键词:乳前喂养,维生素A,发育迟缓,6-59月龄儿童。
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Meta Analysis: Effects of Prelacteal Feeding and Vitamin A Supplementary Intake on Stunting in Children Aged 6-59 Months
Background: Stunting describes the condition of failure to thrive in children under five years old (toddlers) due to chronic malnutrition and recurrent infections, especially in the first 1,000 days of life as a golden period with proper nutrition. This study aimed to examine the effect of prelacteal feeding and vitamin A on the incidence of stunting in children aged 6-59 months using a meta-analysis. Subjects and Method: The meta-analysis was carried out using the PRISMA flowchart and the PICO model. Population: children aged 6-59 months. Intervention: giving prelacteal feeding and vitamin A. Comparison: not giving prelacteal feeding and vitamin A. Outcome: stunting. The online databases used are Google Scholar, ProQuest and Elsevier with the keywords “Stunting” AND “Prelacteal feeding” AND “Vitamin A” AND “Children Aged 6–59 Months” AND “Multivariate” AND “Cross Sectional”. There were 15 cross-sectional studies published in 2013-2023 that met the inclusion criteria. Analysis was performed with RevMan 5.3. Results: A meta-analysis of 15 articles with a cross-sectional study design from different countries, namely Ethiopia, Uganda, Somalia, Indonesia and Sudan in children aged 6-59 months with a total sample of 94,212 research subjects. The results of the meta-analysis showed that there was an effect of not being given prelacteal feeding on the reduced risk of stunting in children aged 6-59 months. Children who were not given prelacteal feeding had 0.57 times the risk of stunting compared to those who were given prelacteal feeding (aOR= 0.57; 95% CI= 0.38 to 0.84; p= 0.005), Children who were not given vitamin A had a risk of being stunted 1.19 times compared to children who were given vitamin A (aOR= 1.19; 95% CI= 1.00 to 1.41; p= 0.050). Conclusion: Children who are not given prelacteal feeding and children who are given vitamin A reduce the risk of stunting in children aged 6-59 months. Keywords: prelacteal feeding, vitamin A, stunting, children aged 6-59 months.
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