1例年轻女性高级别直肠乙状结肠腺癌,无其他特异性,T2n2aM0: 1例报告和文献复习

Evan Savero Widiono, None Martahadinan, Chandra A. Tambunan, Sofa Primatir
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引用次数: 0

摘要

背景:结直肠癌(CRC)是第四大最常见的癌症,其中大多数CRC在50至70岁之间被诊断出来。根据目前的趋势,35-49岁人群的结肠癌和直肠癌发病率可增加124%,20-34岁人群的发病率将分别增加28%和46%。目的:报告一例24岁女性结直肠癌患者。病例报告:一名24岁的女性患者来到北加隆岸市本丹医院急诊室,主诉自1年前出血。在过去6个月内有投诉;病人的体重减轻了20公斤。直肠触诊示肛门括约肌张力正常(+),肛管内可触及肿块,易碎;手套里有粪便和血迹。腹部超声检查发现直肠区域一体积为181cc的实性肿瘤,提示直肠恶性肿瘤。在结肠镜检查中,发现一个圆形,脆弱,易出血的肿瘤,距肛门边缘约1cm,然后进行活检。结肠活检组织病理学检查提示为分化良好的直肠乙状结肠NOS腺癌。患者随后接受了迈尔斯手术技术的手术。手术后患者病情好转,经过一周的治疗,患者可以进行门诊治疗。结论:完整的病史、体格检查和辅助调查对早期发现结直肠癌非常有用,特别是对年轻患者。
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A Young Woman with High-Grade Rectosigmoid Adenocarcinoma, no Other Specified, T2n2aM0: A Case Report and Literature Review
BACKGROUND: Colorectal cancer (CRC) is the fourth most common cancer in which the majority of CRCs are diagnosed between the ages of 50 and 70 years. Based on current trends, the incidence of colon and rectal cancers can increase by 124% in people aged 35–49 years and at the age of 20–34 will increase by 28% and 46%. OBJECTIVES: To report a case of a 24-year-old female patient with CRC. CASE REPORT: A 24-year-old female patient came to the Emergency Room at Bendan Hospital, Pekalongan City, with complaints of bleeding since 1 year ago. There are complaints in the past 6 months; the patient’s weight has decreased by up to 20 kg. Rectal toucher examination revealed normal (+) anal sphincter tone, a palpable mass in the anal canal, and was fragile; there were feces and blood in gloves. Abdominal ultrasonography found a solid tumor mass in the rectum area with a volume of 181 cc, suggesting a malignancy of the rectum. During a colonoscopy, a circular, fragile, and easily bleeding tumor was found, approximately 1 cm from the anal verge, and then biopsy was performed. Histopathological examination of the colon biopsy suggests a well-differentiated, rectosigmoid, NOS adenocarcinoma. The patient then underwent surgery using the Miles procedure technique. The patient’s condition after the operation improved, so after a week of treatment, the patient was able to undergo outpatient treatment. CONCLUSION: A complete history, physical examination, and supporting investigation are very useful in early detection of colorectal carcinoma, especially in young patients.
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期刊介绍: Open Access Macedonian Journal of Medical Sciences (OAMJMS) [formerly known as Macedonian Journal of Medical Sciences] is a top-tier open access medical science journal published by the ID Design 2012/DOOEL Skopje, Rajko Zhinzifov No 48, 1000 Skopje, Republic of Macedonia. OAMJMS is an international, modern, general medical journal covering all areas in the medical sciences, from basic studies to large clinical trials and cost-effectiveness analyses. We publish mostly human studies that substantially enhance our understanding of disease epidemiology, etiology, and physiology; the development of prognostic and diagnostic technologies; trials that test the efficacy of specific interventions and those that compare different treatments; and systematic reviews. We aim to promote translation of basic research into clinical investigation, and of clinical evidence into practice. We publish occasional studies in animal models when they report outstanding research findings that are highly clinically relevant. Our audience is the international medical community as well as educators, policy makers, patient advocacy groups, and interested members of the public around the world. OAMJMS is published quarterly online version. The Open Access Macedonian Journal of Medical Sciences (OAMJMS) publishes Medical Informatics, Basic Science, Clinical Science, Case Report, Brief Communication, Public Health, Public Policy, and Review Article from all fields of medicine and related fields. This journal also publishes, continuously or occasionally, the bibliographies of the members of the Society, medical history, medical publications, thesis abstracts, book reviews, reports on meetings, i­n­formation on future meetings, important events and dates, and various headings which contribute to the development of the corresponding scientific field.
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