Mind-altering Cycads? Preliminary Evidence of Psychoactive Effects in Cycadales

This article examines historical and contemporary evidence for the importance of cycads as sources of psychoactive experiences for ritual and recreational purposes. Methods used include critical analysis and comparison of published and gray literature as well as ethnographic accounts gathered by the author in Mexico and South Africa. The consumption of cycad parts (pollen, coralloid root, and caudex) to derive an intentional psychoactive effect as a drug may implicate the neurotoxic amino acid BMAA, while fermentation and distillation of cycad starch result in intoxication from alcohol. Cycad ingestion is related to medicinal uses, magico-religious practice, and sexual stimulation as an aphrodisiac. Interconnections between these functions, the ceremonial importance of cycads, and conservation implications are discussed. Conclusions include the need to better understand effects on users and on cycad populations, and the potential pitfalls and opportunities psychoactive uses present for community-based conservation.