呼吸暂停患者慢波睡眠与血氧饱和度的关系:回顾性研究

Q4 Medicine Sleep Medicine Research Pub Date : 2023-09-30 DOI:10.17241/smr.2023.01725
Ebrahim Norouzi, Ali Zakei, Alexandra J. Bratty, Habibolah Khazaie
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引用次数: 0

摘要

背景与目的已有研究表明,阻塞性睡眠呼吸暂停(OSA)患者的慢波睡眠(SWS)受到干扰。然而,目前尚不清楚SWS的降低是否与呼吸异常或最低氧饱和度确定的OSA程度有关。此外,氧饱和度与SWS之间的关系研究有限。本研究探讨了OSA患者SWS与最低血氧饱和度之间的关系。方法589例OSA患者(平均年龄48.54岁)完成通宵多导睡眠描记术。结果结果显示,三个呼吸暂停低通气指数(AHI)组的SWS评分(轻度呼吸暂停为5-15分,中度呼吸暂停为16-30分,重度呼吸暂停为>30分)存在显著差异。重度呼吸暂停组SWS评分较低。此外,结果表明,随着氧饱和度的降低,SWS评分降低。结论本研究结果表明,血氧饱和度可显著预测SWS的数量。这些发现表明,低氧饱和度的干预可以增加SWS的数量。这些发现的临床后果值得考虑。
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The Relationship Between Slow Wave Sleep and Blood Oxygen Saturation Among Patients With Apnea: Retrospective Study
Background and Objective Prior research suggests that slow wave sleep (SWS) is disrupted in people with obstructive sleep apnea (OSA). However, it was not clear whether the reduction in SWS is related to abnormal breathing or the extent of OSA as determined by the minimum oxygen saturation. Further, there is limited research on the relationship between oxygen saturation and SWS. The present study examined the relationship between SWS and minimum oxygen saturation levels in patients with OSA.Methods The sample consisted of 589 patients with OSA (mean age: 48.54 years) who completed full-night polysomnography.Results Results showed that there was a significant difference in SWS scores across three apnea-hypopnea index (AHI) groups (AHI score 5–15 for mild apnea, 16–30 for moderate apnea, and >30 for severe apnea). Lower SWS scores were observed in the severe apnea group. Additionally, results indicated that as oxygen saturation decreased, the SWS scores decreased.Conclusions Results from this study indicate that oxygen saturation significantly predicts SWS amounts. These findings suggest that interventions for low oxygen saturation could enhance the amounts of SWS. The clinical ramifications of these findings are worthy of consideration.
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来源期刊
Sleep Medicine Research
Sleep Medicine Research Medicine-Neurology (clinical)
CiteScore
0.90
自引率
0.00%
发文量
20
审稿时长
8 weeks
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