孟加拉国某三级医院COVID-19患者预后分析

Khan Mohammad Arif, Abhijit Datta, None Sharifunnesa, Mohammad Mahfuzul Haque Mollah, Gazi Md Mahmudul Hassan, None Nusrat Jahan Binti, Mst Sabira Sultana, Jaya Bishnu
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摘要

2019冠状病毒病(COVID-19)已在孟加拉国蔓延。本研究旨在详细描述2020-2021年期间在孟加拉国法里德普尔的Bangabandhu Sheikh Mujib医学院医院住院的COVID-19患者的结果。这项前瞻性观察性研究评估了500名COVID-19住院患者的结局。本研究纳入了经鼻咽拭子逆转录酶聚合酶链反应(RT-PCR)阳性报告证实的COVID-19患者。采用世界卫生组织提供的7分顺序量表对患者的预后进行评价。受访者平均年龄45.70(±14.50)岁。500例患者中,男性331例(66.2%),女性169例(33.8%)。常见合并症为超重或肥胖191例(38.2%)、高血压173例(34.6%)、糖尿病163例(32.6%)、吸烟90例(18.0%)、缺血性心脏病70例(14.0%)、哮喘36例(7.2%)、慢性阻塞性肺疾病(COPD) 28例(5.6%)、慢性肾脏疾病(CKD) 18例(3.6%)、中风12例(2.4%)、恶性肿瘤6例(1.2%)、慢性肝病5例(1.0%)。500例患者中,轻度238例(47.6%),中度124例(24.8%),重度130例(26.0%),危重型8例(1.6%)。299例(59.8%)患者需要面罩或鼻尖低流量供氧,64例(12.8%)患者需要高流量(无创)供氧,1例(0.2%)患者需要无创通气(NIV)。住院时间显著(p<吸烟者(12.68±8.672天)高于非吸烟者(9.79±6.007天)。出院时或出院后不久,206例(41.2%)患者不能恢复正常的日常生活活动。仅有9例(1.8%)患者在医院死亡。Bangabandhu Sheikh Mujib Med. col。[j]; 2009;2(1): 22-28
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Outcomes of Patients with COVID-19 in a Tertiary Care Hospital of Bangladesh
Coronavirus Disease-2019 (COVID-19) has disseminated throughout Bangladesh. This study aimed to provide a detailed account of outcomes of patients with COVID-19 who were hospitalized during 2020-2021 in Bangabandhu Sheikh Mujib Medical College Hospital, Faridpur, Bangladesh. This prospective observational study evaluated outcomes of 500 hospitalized patients with COVID-19. Patients with COVID-19, confirmed by positive Reverse Transcriptase Polyremase Chain Reaction (RT-PCR) reports of nasopharyngeal swab were enrolled in this study. Outcomes of the patients were evaluated by 7-point ordinal scale provided by World Health Organization. Mean age of the respondents was 45.70 (±14.50) years. Out of 500 patients, 331 (66.2%) were male and 169 (33.8%) were female. Common comorbidities were overweight or obesity (191, 38.2%), hypertension (173, 34.6%), diabetes mellitus (163, 32.6%), smoking (90, 18.0%), ischemic heart disease (IHD) (70, 14.0%), asthma (36, 7.2%), chronic obstructive pulmonary disease (COPD) (28, 5.6%), chronic kidney disease (CKD) (18, 3.6%), stroke (12, 2.4%), malignancy (6, 1.2%) and chronic liver disease (CLD) (5, 1.0%). Out of 500 patients, 238 (47.6%) patients had mild disease, 124 (24.8%) patients had moderate disease, 130 (26.0%) patients had severe disease and 8 (1.6%) patients developed critical COVID-19. Among the respondents, 299 (59.8%) patients required low flow oxygen by face mask or nasal prongs, 64 (12.8%) patients required high flow (non-invasive) oxygen therapy, 1(0.2%) patient required non-invasive ventilation (NIV). Duration of hospital stay was significantly (p< 0.05) higher in smokers (12.68±8.672 days) than non-smokers (9.79± 6.007 days). During or soon after discharge, 206 (41.2%) patients could not resumed normal activities of daily life. Only 9 (1.8%) patients died at hospital. Bangabandhu Sheikh Mujib Med. Coll. J. 2023;2(1): 22-28
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