高血压合并阻塞性睡眠呼吸暂停的流行病学及临床分析

Solange Flore Ngamami Mongo, Kivie Mou-Moue Ngolo Letomo, Arnold Sem Nguia Vel, Christian Kouala Landa, Franck Yannis Kouikani, Rogue Pattern Bakekolo, Bertrand Fikahem Ellenga Mbolla
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摘要

目的:采用柏林问卷(Berlin questionnaire)检测高血压患者的阻塞性睡眠呼吸暂停综合征(OSAS),并建立患者的流行病学和临床资料。患者和方法:这是一项横断面分析研究,于2019年3月至8月在布拉柴维尔CHU进行。包括门诊随访的高血压患者。OSAS的诊断是基于对柏林问卷的回答。结果:共纳入315例患者,其中女性210例(64.9%)。OSAS患病率为75.8% (n = 239)。睡眠呼吸暂停患者的平均年龄为58.5±12.4岁,以女性为主(64.9%)。在混合分析中,与(OSAS)相关的因素为:职业OR (2.56) 95% CI(1.15 - 5.69),肥胖OR(7.50)(1.60 - 35.1)和腹部肥胖OR (2.36 CI 95%(1.36 - 4.08)。59个国家(18.7%)的生活水平很高。既往住院病史209例(66.3%),糖尿病95例(30.2%),心力衰竭57例(18.1%)。生活方式:久坐(n = 181;57.5%)饮酒(n = 97;30.8%)。体检中超重96例(30.5%),肥胖91例(28.8%)。Berlin问卷的异常情况为:打鼾(n = 197;62.5%)、清醒疲劳(n = 127;40.3%),白天疲劳(n = 97;30.8%)。结论:阻塞性睡眠呼吸暂停综合征在高血压患者中的患病率较高。因此,有必要通过多导睡眠仪来探索睡眠,并通过与相关风险因素作斗争来预防。
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Epidemiological and Clinical Profile of Hypertensive Patients with Obstructive Sleep Apnea at CHU-B
Objectives: To detect obstructive sleep apnea syndrome (OSAS) in a population of hypertensive patients, using the Berlin questionnaire and to establish the epidemiological and clinical profile of patients. Patients and Method: This was a cross-sectional and analytical study, carried out from March to August 2019 at the CHU Brazzaville. Included are hypertensive patients followed as outpatients. The diagnosis of the OSAS was based on the answers to the Berlin questionnaire. Results: A total of 315 patients were included, including 210 women (64.9%). Prevalence of OSAS was 75.8% (n = 239). The average age of patients with sleep apnea was 58.5 ± 12.4 years with female predominance (64.9%). In the mixed analysis, the factors associated with (OSAS) were: occupation OR (2.56) 95% CI (1.15 - 5.69), obesity OR 7.50 (1.60 - 35.1) and abdominal obesity OR 2.36 CI 95% (1.36 - 4.08). Living standards were high in 59 cases (18.7 per cent). The medical history of previous hospitalization was present in 209 cases (66.3%), diabetes 95 (30.2%), and heart failure 57 cases (18.1%). Lifestyle patterns were: sedentary (n = 181; 57.5%) alcohol consumption (n = 97; 30.8%). On physical examination, overweight was noted in 96 cases (30.5%) and obesity in 91 cases (28.8%). The anomalies in the Berlin questionnaire were: snoring (n = 197; 62.5%), waking fatigue (n = 127; 40.3%), fatigue during the day (n = 97; 30.8%). Conclusion: The prevalence of obstructive sleep apnea syndrome is high during arterial hypertension in our setting. Hence the need for sleep exploration through polysomnography, and prevention through the fight against the associated risk factors.
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