口腔黏膜下纤维化的当前管理策略

Dr. Simran D. Badki, Dr. Vidya K. Lohe, Dr. Rahul Bhowate, Dr. Suwarna Dangore, Dr. Mrunal Meshram, Dr.Pragati Bhargava
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引用次数: 0

摘要

口腔黏膜下纤维化是一种恶性前病变,最近被认为是“槟榔引起的口腔纤维化”。它是一种“不可逆转的慢性疾病,影响患者的口腔和全身健康”。然而,槟榔或槟榔是口腔粘膜下纤维化(OSMF)的主要病因;其他因素,如过量摄入辣椒、营养缺乏和免疫因素也被认为是导致这种疾病的因素。它会引起黏膜下组织的炎症和纤维化,导致牙关紧闭和口腔黏膜僵硬。这种疾病的治疗包括许多保守、药物和手术治疗;然而,没有一种治疗方式被证明是一种标准的治疗选择。草药治疗被认为在OSMF治疗中更有效。不幸的是,关于OSMF管理的文献不能一次性公正地对待所有的治疗方式。OSMF的新趋势和治疗方式不断增加,但由于多因素病因,疾病的复杂性和治疗趋势的变化,制定完美的OSMF治疗方案仍然是牙科临床医生面临的挑战。本综述旨在启发临床医生了解当前的疾病情况,并试图包括所有最新的治疗方式。目的是回顾和评估这种疾病的现状,并简要介绍不同可用治疗方式的疗效,以帮助牙科医生制定治疗方案,了解每种方式的适当效果、优缺点,并为OSMF的潜在未来治疗选择提供启发。
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Current Management Strategies in Oral Submucous Fibrosis
Oral sub-mucous fibrosis is a premalignant condition recently recognized as "areca nut-induced oral fibrosis." It is "achronic disease which is irreversible, affecting oral and systemic health of patients." However, Areca nut or betel nut is the primaryetiologic reason for Oral Submucous fibrosis (OSMF); other factors like excess chilies intake, nutritional deficiencies, andimmunological factors are also considered causative agents for the disease. It causes inflammation and fibrosis of the submucosaltissues causing trismus and rigid oral mucosa. The treatment for this disorder includes numerous conservative, medicinal, andsurgical management; however, no treatment modality has been proven to be a standard treatment option. Herbal modalities areseen to be more effective in OSMF treatment. Unfortunately, the literature on the management of OSMF cannot do justice to allthe treatment modalities at one stop. The new trends and treatment modalities for OSMF keep adding up from time to time, andyet formulating the perfect treatment protocol for OSMF management is still challenging for dental clinicians due to themultifactorial etiology, complexity of the disease, and changing trends in treatment. The present review aimed to enlighten cliniciansabout the current disease scenario and tried to include all the latest treatment modalities. The objectives are to review and assessthe existing situation of this disease with a brief on the efficacy of different available treatment modalities used to help dentalphysicians formulate a treatment protocol with knowing the proper effects, advantages, and disadvantages of each modality andenlightening the potential future treatment options for OSMF.
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