手部握力作为慢性肝病患者肌肉减少的一种方式

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摘要

目的:探讨慢性肝病患者握力正常与异常的频率。方法:本描述性横断面研究在巴基斯坦白沙瓦开伯尔教学医院医学系进行。数据是在机构伦理委员会批准后,从2020年10月到2021年4月的六个月内收集的。每个参与者在被纳入研究之前都给予了知情同意。共纳入254例患者。每位患者被要求按照设定的标准用惯用手握住手部测力计。三次读数之间的休息时间为10秒,以公斤为单位的最高读数为最终读数。使用卡尺(Lange®)测量肱三头肌皮肤褶皱(TSF)和拇内收肌(APMT)的厚度。测量TSF和腹围(AC)的人体测量值,并测量臂中肌围(MAMC)。结果:254例患者平均年龄48±10.59岁,其中男性145例(57%),女性109例(43%)。此外,125例(49%)患者的手握力正常,129例(51%)患者的手握力异常。平均APMT为16.5±3.4 mm,平均MAMC为24.2±3.7 cm,平均TSF为15±13.11 mm。结论:半数以上慢性肝病患者存在握力异常。HGS试验是一种方便、经济的床边工具,用于检测慢性肝病患者的肌肉减少症。
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HAND GRIP STRENGTH AS A MODALITY FOR SARCOPENIA IN PATIENTS WITH CHRONIC LIVER DISEASES
Objective: To determine the frequency of normal and abnormal handgrip strength in patients with chronic liver disease.Methodology: This descriptive cross-sectional study has been conducted in the Department of Medicine Khyber Teaching Hospital in Peshawar, Pakistan. Data was collected over six months, from October 2020 to April 2021 after the approval by the institutional ethical board. Each participant gave informed consent before being included in the study. A total of 254 patients were included. Every patient was asked to hold the Hand Dynamometer in the dominant hand as per the set criteria. Three readings were taken with a resting period of ten seconds between each, and the highest reading in kilograms was considered final. Calliper (Lange®) was used to measure the thickness of the Triceps skin fold (TSF) and Adductor pollicis muscle (APMT). The anthropometric value of TSF and abdominal circumference (AC) was taken, and measurements were also made of the mid-arm muscle circumference (MAMC).Results: Among 254 patients, the mean age was 48 ± 10.59 years while145 (57%) patients were male, while 109 (43%) were female. Moreover, 125 (49%) patients had normal handgrip strength (HGS), while 129 (51%) had abnormal handgrip strength. The mean APMT was 16.5 ± 3.4 mm, the mean MAMC 24.2 ± 3.7 cm, and the mean TSF was 15 ± 13.11 mm.Conclusion: Abnormal handgrip strength was reported in more than half of patients with chronic liver disease. HGS test is a convenient and cost-effective bedside tool to determine sarcopenia in chronic liver disease patients.
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