间日疟原虫疟疾患儿神经系统并发症的评估

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摘要

目的:评估白沙瓦某三级医院儿童间日疟原虫疟疾的神经系统并发症。方法:这项描述性横断面研究于2021年4月至2021年9月在白沙瓦Hayatabad医疗中心儿科进行。采用方便抽样的方法,共纳入门诊高热、恶心、腹泻和头痛患者183例,显微镜下确诊为单间日疟原虫感染。预先设计的表演用于提取有关人口统计学,实验室调查和神经系统并发症的信息。采用SPSS (version 21.0)软件进行统计分析。结果:183例患者中男性占71.6%。患者平均年龄为6.44±2.46岁,平均体重为12.76±4.56 kg。平均病程为6.14±2.18天。实验室检查显示,血红蛋白和血小板计数低分别为38.8%和42.2%。15.8%的儿童出现神经系统并发症,与性别、年龄组和病程(分层)无显著相关性,与血红蛋白、红细胞压积水平和血小板计数分层显著相关。结论:间日疟原虫确诊后出现神经系统并发症的儿童较少。此外,这些并发症与血红蛋白分层、红细胞压积水平和血小板计数显著相关。
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ASSESSMENT OF NEUROLOGICAL COMPLICATIONS IN CHILDREN PRESENTING WITH PLASMODIUM VIVAX MALARIA
Objective: To assess neurological complications in children presenting with Plasmodium vivax malaria at a Tertiary Care Hospital of Peshawar.Methodology: This descriptive cross sectional study was carried out in the Pediatric Department, Hayatabad Medical Complex, Peshawar from April 2021 to September 2021. A total of 183 patients were enrolled using convenient sampling from outpatient department with high grade fever, nausea, diarrhea, and headache, duly confirmed for Plasmodium vivax mono-infection microscopically. A pre-designed performa was used to extract information regarding demographics, laboratory investigations, and neurological complications. SPSS (version 21.0) was used to check the statistics.Results: Out of 183 cases 71.6% were male. The mean age of the patients was 6.44±2.46 years, while mean weight was 12.76±4.56 kg. In mean duration of disease, it was recorded to be as 6.14±2.18 days. The laboratory investigations showed, low level of hemoglobin and platelets count in 38.8% and 42.2% respectively. Neurological complications were detected in 15.8% of children and were non significantly associated with gender, age group and duration of disease (stratified), and was significantly associated with the stratification of hemoglobin, hematocrit levels and platelets count.Conclusion: A less frequent number children reported to have neurological complications when diagnosed with P. vivax. Furthermore, these complications are associated significantly with the stratification of hemoglobin, hematocrit levels and platelets count.
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