跨性别患者保留生育能力的选择:综述

IF 0.4 Q4 MATHEMATICS, APPLIED Trudy Instituta Matematiki i Mekhaniki UrO RAN Pub Date : 2023-10-08 DOI:10.3390/uro3040024
Natalie Mainland, Dana A. Ohl, Ahmed R. Assaly, Nabila Azeem, Amber Cooper, Angie Beltsos, Puneet Sindhwani, Tariq A. Shah
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引用次数: 0

摘要

生育保存技术已经存在了几十年,并且该领域正在迅速发展;关于跨性别患者使用这些技术的数据有限。对于希望在变性前保留生育能力的变性患者,有很多选择。这些选择包括配子、胚胎或卵巢组织的冷冻保存。目前,射精或睾丸精子、未成熟卵母细胞和卵巢组织可以保存以供以后使用,但未成熟睾丸组织没有这样的使用选择。许多经济、社会和法律障碍以及医生和患者缺乏意识也阻碍了这些生育保留服务的利用。虽然选项丰富,但使用率相对较低。关于成功使用保存组织的初步数据看起来很有希望,其出生率与非变性患者没有什么不同。需要对这一领域进行进一步调查。此外,在过渡治疗之前,关于保留生育能力选择的咨询应成为提供者与患者对话的重要组成部分。
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Fertility Preservation Options for Transgender Patients: An Overview
Fertility preservation technologies have existed for decades, and the field is rapidly advancing; limited data exist regarding the use of these technologies by transgender patients. Many options are available for transgender patients who wish to preserve fertility before transitioning. These options include the cryopreservation of gametes, embryos, or ovarian tissue. Currently, ejaculated, or testicular sperm, immature oocytes, and ovarian tissue can be preserved for later use, but no such use option exists for immature testicular tissue. Many financial, sociological, and legal barriers and a lack of awareness among physicians and patients also hinders the utilization of these fertility preservation services. While options are abundant, usage rates are relatively low. The initial data regarding the successful use of preserved tissues appears promising, with birth rates not dissimilar to non-transgender patients. Further investigations into this area are needed. In addition, counseling regarding fertility preservation options should become a significant part of the provider-patient conversation before transitioning therapies.
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CiteScore
0.80
自引率
20.00%
发文量
67
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