甘菊对腹腔镜胆囊切除术后恶心呕吐的影响:一项三盲随机临床试验

Soheila BAKHTIARI, Gholamreza KHALILI, Razieh Salimi ZADAK
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引用次数: 0

摘要

本研究旨在评价洋甘菊对腹腔镜胆囊切除术后恶心呕吐的影响。洋甘菊(L.)随机分为甘菊组和安慰剂组。手术前1小时进行干预。恶心的严重程度和呕吐的频率用视觉模拟量表测量。两组患者分别在术前、术后恢复期和术后2 h三个阶段进行研究。数据采用描述性和分析性统计(SPSS)进行分析。两组患者恶心的平均严重程度均随时间显著增加;然而,与安慰剂组相比,洋甘菊组的这种增加明显轻微。在康复出院前,洋甘菊组和安慰剂组的术前恶心发生率分别为6.2%和25%。2小时后,在外科病房,估计洋甘菊组的这一频率为31.2%,安慰剂组为75% (P <0.05)。洋甘菊组和安慰剂组的外科病房呕吐频率分别为15.6%和56.2%。因此,洋甘菊组的这一频率显著低于安慰剂组(P<0.001)。似乎在腹腔镜手术中,使用洋甘菊滴剂作为预防药物可以减少术后恶心和呕吐。
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The effect of chamomile on nausea and vomiting after laparoscopic cholecystectomy: A triple-blind randomized clinical trial
The present study aimed to evaluate the effect of Chamomilla Recutita on nausea and vomiting after laparoscopic cholecystectomy. Chamomilla Recutita (L.) fell into either chamomile or placebo groups randomly. The intervention was performed one hour before the operation. The severity of nausea and the frequency of vomiting was measured using a visual analog scale. Both groups were studied in three stages before the operation, after the operation in recovery, and 2 hours after the operation. Data were analyzed using descriptive and analytical statistics (SPSS). The mean severity of nausea increased significantly over time in both groups; however, this increase was significantly slighter in the chamomile group than that in the placebo group. The frequency of preoperative nausea in the chamomile and placebo groups was 6.2% and 25%, respectively, before being discharged from the recovery. Two hours later, in the surgical ward, this frequency was estimated to be 31.2% in the chamomile group and 75% in the placebo group (P <0.05). The frequency of vomiting in the surgical ward was 15.6% and 56.2% in the chamomile and placebo groups, respectively. Thus, this frequency in the chamomile group was significantly lower than in the placebo group (P<0.001). It seems that in laparoscopic surgeries, the use of chamomile drops as a preventive drug reduces postoperative nausea and vomiting.
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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
32
期刊介绍: The Tokai Journal of Experimental and Clinical Medicine, also referred to as Tokai Journal, is an official quarterly publication of the Tokai Medical Association. Tokai Journal publishes original articles that deal with issues of clinical, experimental, socioeconomic, cultural and/or historical importance to medical science and related fields. Manuscripts may be submitted as full-length Original Articles or Brief Communications. Tokai Journal also publishes reviews and symposium proceedings. Articles accepted for publication in Tokai Journal cannot be reproduced elsewhere without written permission from the Tokai Medical Association. In addition, Tokai Journal will not be held responsible for the opinions of the authors expressed in the published articles.
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