儿童胸部计算机断层扫描相关癌症的终生归因风险(LAR)评估

Q3 Health Professions Frontiers in Biomedical Technologies Pub Date : 2023-09-29 DOI:10.18502/fbt.v10i4.13726
Mohammad Hossein Jamshidi, Aida Karami, Jalal Ordoni, Salar Bijari
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引用次数: 0

摘要

目的:低剂量辐射的危险是线性持续的,没有阈值,调查得出结论,尽管计算机断层扫描(CT)的癌症风险很低,但它不是零。本研究旨在确定儿童单次胸部CT扫描患者的辐射剂量,并估计癌症发病率的终生归因风险(LAR)。材料与方法:将1105名儿童分为0岁、5岁、10岁、15岁4个年龄组。将胸部CT扫描的剂量学数据插入VirtualDoseCT软件,计算器官剂量和有效剂量。基于器官剂量的癌症风险是根据BEIR VII报告估计的。结果:男孩的最高剂量与肺(5.13 ~ 6.8 mSv)和心脏(5.27 ~ 5.97 mSv)有关,女孩的最高剂量与肺(4.98 ~ 5.91 mSv)、乳房(4.24 ~ 5.21 mSv)和心脏(4.9 ~ 5.71 mSv)有关。肺癌发生率最高的是0岁年龄组的乳房(61.01 / 10万),其次是5岁年龄组的乳房(46.16 / 10万)和0岁年龄组的肺部(43.32 / 10万)。结论:本研究对儿童胸部CT扫描的辐射剂量以及有效剂量和器官剂量值增加癌症风险的程度有了更好的认识。
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Estimation of Lifetime Attributable Risk (LAR) of Cancer Associated with Chest Computed Tomography Procedures in Children
Purpose: The danger of radiation at low doses continues linearly, and without a threshold, investigations concluded that although the risk of cancer from Computed Tomography (CT) scans is low, it is not zero. This study aims to determine the patient's radiation dose and estimate the Lifetime Attributable Risk (LAR) of cancer incidence for a single chest CT scan in children. Materials and Methods: We divided 1,105 children into four age groups: 0 years, 5 years, 10 years, and 15 years. Dosimetric data of chest CT scan were plugged in VirtualDoseCT software, and organ dose and effective dose were calculated. The cancer risk based on organ dose is estimated according to the BEIR VII report. Results: The highest dose in boys was related to lung (5.13 - 6.8 mSv) and heart (5.27-5.97 mSv), and in girls, lung (4.98 - 5.91 mSv), breast (4.24 - 5.21 mSv), and heart (4.9 - 5.71 mSv) had the highest dose. The highest LAR (per 100,000) was obtained for the breast in the age group of 0 years (61.01), followed by the breast for the age group of 5 years (46.16) and lung in the age group of 0 years (43.32) in girls. Conclusion: This study shows a better concept of radiation dose in the chest CT scan in children and how much effective dose and organ dose values increase the cancer risk.
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来源期刊
Frontiers in Biomedical Technologies
Frontiers in Biomedical Technologies Health Professions-Medical Laboratory Technology
CiteScore
0.80
自引率
0.00%
发文量
34
审稿时长
12 weeks
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