体外循环中机械通气对术后肺部并发症的影响

Ranko Zdravkovic, Milanka Tatic, Miodrag Golubovic, Mihaela Preveden, Marija Klinovski, Sanja Vickovic
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摘要

介绍。在无泵心脏手术中,当体外循环开始或潮气量低时停止机械通气是常见的做法。本研究的目的是探讨低潮气量通气的患者在体外循环期间是否比不通气的患者有更低的术后肺部并发症百分比。材料和方法。这项回顾性研究包括接受冠状动脉搭桥手术14个月的患者。肺部疾病患者和射血分数高的患者;30%被排除在研究之外。结果。该研究共纳入499名患者。其中398例采用低潮气量通气,101例体外循环时不通气。两组在基线特征、合并症和术中数据上没有差异。两组肺部并发症发生率相同(通气16%,不通气17.8%)。最常见的是需要长时间机械通气(通气5.8%,不通气5.9%)和胸腔积液(通气4.8%,不通气5.9%)。两组的肺炎发病率相同(2%)。其他并发症较少。术后机械通气时间、重症监护病房住院时间和住院死亡率在两组间无显著差异。结论。心脏手术后的肺部并发症仍然很常见。我们的临床经验表明,体外循环中机械通气策略的选择对术后肺部并发症没有影响。
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Effects of mechanical ventilation during cardiopulmonary bypass on postoperative pulmonary complications
Introduction. It is common practice in on-pump cardiac surgery to stop mechanical ventilation when extracorporeal circulation is started or to continue with low tidal volumes. The aim of this study was to investigate whether patients ventilated with low tidal volumes had a lower percentage of postoperative pulmonary complications compared to patients who were not ventilated during cardiopulmonary bypass. Material and Methods. This retrospective study included patients who underwent coronary artery bypass graft surgery over a period of 14 months. Patients with lung diseases and those with an ejection fraction < 30% were excluded from the study. Results. A total of 499 patients were included in the study. Of these, 398 were ventilated with low tidal volumes, while 101 patients were not ventilated during extracorporeal circulation. The groups did not differ in baseline characteristics, comorbidities, and intraoperative data. Pulmonary complications were equally prevalent in both groups (ventilated 16%, not ventilated 17.8%). The most frequent were the need for prolonged mechanical ventilation (ventilated 5.8%, not ventilated 5.9%), and pleural effusions (ventilated 4.8%, not ventilated 5.9%). The incidence of pneumonia was identical in both groups (2%). Other complications were less frequent. Duration of mechanical ventilation after surgery, stay in the intensive care unit, and in-hospital mortality did not differ significantly between the groups. Conclusion. Pulmonary complications after cardiac surgery are still common. The experience at our clinic showed that the choice of mechanical ventilation strategy during cardiopulmonary bypass does not affect postoperative pulmonary complications.
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