一般人群和医学专业人员对诱导多能干细胞知识的评估

Sanja Rascanin, Mirjana Jovanovic, Nemanja Rancic
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摘要

介绍。诱导多能干细胞在伦理上比胚胎干细胞更容易被接受。本文的目的是评估普通人群和医学专业人员对这些细胞的了解,因为这可能会影响进一步的研究。材料和方法。我们进行了一项调查,以评估一般人群和医务工作者对诱导多能干细胞的知识。纳入标准是年龄在18岁以上,具有塞尔维亚语读写能力。该调查通过电子邮件和印刷材料进行,使用有效的问卷来评估对诱导多能干细胞的捐赠、储存和应用的认识、知识和态度。将收集到的数据输入Excel数据库,并使用statistical Package for The Social Sciences version 26.0进行完整的统计分析。结果。卫生工作者的正确率为17.5% ~ 67.1%,一般人群的正确率为16.4% ~ 49.4%。在卫生工作者人群中,每个应答者的平均正确回答次数为6次,而在一般人群中为4次,这在统计上明显较低。结论。研究结果表明,医护人员对诱导多能干细胞的知识水平高于一般人群,但知识水平受教育水平、信息可得性、社会经济地位、思想观念和保守态度的影响。
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Evaluation of knowledge on induced pluripotent stem cells among the general population and medical professionals
Introduction. Induced pluripotent stem cells are ethically much more acceptable than embryonic stem cells. The aim of this paper is to evaluate the knowledge on these cells among the general population and medical professionals, because this may influence further research. Material and Methods. We conducted a survey to assess knowledge on induced pluripotent stem cells among the general population and medical workers. The inclusion criteria were age over 18 years and the ability to read and write in Serbian. The survey was conducted via email and printed materials using a validated questionnaire for evaluation of awareness, knowledge, and attitudes towards donation, storage, and application of induced pluripotent stem cells. The collected data were entered into an Excel database, and complete statistical analysis was performed using the Statistical Package for the Social Sciences version 26.0. Results. The rate of correct answers among health workers ranged from 17.5% to 67.1%, and among the general population from 16.4% to 49.4%. The average number of correct answers per respondent in the population of health workers was 6, while in the general population it was 4, which is statistically significantly lower. Conclusion. The research results showed that healthcare workers have a higher level of knowledge on induced pluripotent stem cells than members of the general population, but the level of knowledge can be influenced by the level of education, availability of information, socioeconomic status, ideology, and conservative attitudes.
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