Igor Barbosa Lima, Betania Mara Alvarenga, Priscila Izabel Santos de Tótaro, Fernanda Boratto, Elaine Amaral Leite, Pedro Pires Goulart Guimaraes
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Improved Antiproliferative Activity of Doxorubicin-Loaded Calcium Phosphate Nanoparticles Against Melanoma Cells
HIGHLIGHTS N-Dox has higher activity against A-375 cells than free doxorubicin. The formulation has higher selectivity indices than free doxorubicin. Treatment induced senescence and no colonies recovered after short-term exposure.
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