{"title":"[给药四甲基硫脲和n -亚硝基二乙胺后大鼠肝细胞中异有机抗原——肾性非组蛋白染色体蛋白的表达]。","authors":"A A Klimova","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Tetramethylthiuramdisulfide (TMTD) decreasing the formation of hepatomas in inbred rats with the subsequent intraperitoneal administration of nitrosodiethylamine (NDEA) is established not to affect the NDEA-induced expression of the heteroorganic antigens of nonhistone chromosomal proteins of the kidney nature associated with the hepatoma and regenerating liver cells of rats. It is supposed that changes in the NDEA metabolism induced by the preceeding action of TMTD, obviously, do not influence the hepatocarcinogenic potencies relative to stimulation of cell proliferation.</p>","PeriodicalId":77530,"journal":{"name":"Eksperimental'naia onkologiia","volume":"12 4","pages":"76-7"},"PeriodicalIF":0.0000,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Expression of hetero-organic antigens--nonhistone chromosomal proteins of renal nature in liver cells of rats after administration of tetramethylthiuram disulfide and N-nitrosodiethylamine].\",\"authors\":\"A A Klimova\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Tetramethylthiuramdisulfide (TMTD) decreasing the formation of hepatomas in inbred rats with the subsequent intraperitoneal administration of nitrosodiethylamine (NDEA) is established not to affect the NDEA-induced expression of the heteroorganic antigens of nonhistone chromosomal proteins of the kidney nature associated with the hepatoma and regenerating liver cells of rats. It is supposed that changes in the NDEA metabolism induced by the preceeding action of TMTD, obviously, do not influence the hepatocarcinogenic potencies relative to stimulation of cell proliferation.</p>\",\"PeriodicalId\":77530,\"journal\":{\"name\":\"Eksperimental'naia onkologiia\",\"volume\":\"12 4\",\"pages\":\"76-7\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1990-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Eksperimental'naia onkologiia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Eksperimental'naia onkologiia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Expression of hetero-organic antigens--nonhistone chromosomal proteins of renal nature in liver cells of rats after administration of tetramethylthiuram disulfide and N-nitrosodiethylamine].
Tetramethylthiuramdisulfide (TMTD) decreasing the formation of hepatomas in inbred rats with the subsequent intraperitoneal administration of nitrosodiethylamine (NDEA) is established not to affect the NDEA-induced expression of the heteroorganic antigens of nonhistone chromosomal proteins of the kidney nature associated with the hepatoma and regenerating liver cells of rats. It is supposed that changes in the NDEA metabolism induced by the preceeding action of TMTD, obviously, do not influence the hepatocarcinogenic potencies relative to stimulation of cell proliferation.
分享
京公网安备 11010802042870号
京ICP备2023020795号-1
求助内容：
应助结果提醒方式：
扫码关注我们
