预防术后肺部并发症的术前肺部评估

Mehmet Eren Tuna, Metin Akgün
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引用次数: 0

摘要

术后肺部并发症(PPCs)由患者、手术和麻醉相关因素的复杂相互作用引起。尽管肺部并发症具有重大影响,但目前还没有标准化指南建议采用全面的术前方法来评估具有肺部并发症风险因素的患者。术前肺部评估(PPE)在确定患者潜在病情、未确诊疾病和最佳治疗方法方面起着关键作用。PPE 包括对患者、手术和麻醉相关风险因素的系统识别。严重的 PPC 包括肺不张、肺炎、呼吸衰竭、肺栓塞和慢性肺病恶化。手术的紧迫性、类型、持续时间、手术方法和合并症都会影响 PPC 的发生率,其中心脏、胸部、腹部和血管手术尤其容易发生 PPC。人口老龄化增加了手术需求,高龄和体弱预示着更高的发病率和死亡率风险。充血性心力衰竭、肥胖、阻塞性睡眠呼吸暂停和吸烟等疾病增加了肺部手术的风险。哮喘、慢性阻塞性肺疾病、间质性肺疾病、肺动脉高压、既往肺血栓栓塞症、急性呼吸道感染和 COVID-19 都会影响肺部风险。手术和麻醉相关的风险因素包括手术部位、手术时间和急诊手术。靠近膈肌的手术会增加 PPC 风险,而手术时间越长,PPC 发生率越高。急诊手术给风险评估带来了挑战。麻醉技术会影响手术效果,区域麻醉通常更可取。由于目前的文献缺乏全面的 PPE 方法,我们在这篇综述中介绍了手术患者术前肺部处理的综合方法,以帮助进行风险分层、进一步优化,以及在同意进行大型手术之前,外科医生与患者及其家属共同做出决策。
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Preoperative pulmonary evaluation to prevent postoperative pulmonary complications

Postoperative pulmonary complications (PPCs) arise from a complex interplay of patient, surgical, and anesthesia-related factors. Despite their significant impact, there are currently no standardized guidelines recommending a comprehensive preoperative approach to assessing patients with PPC risk factors. Preoperative pulmonary evaluation (PPE) plays a pivotal role in identifying underlying patient conditions, undiagnosed diseases and optimal treatments. PPE involves systematic identification of patient, surgical, and anesthesia-related risk factors. Severe PPCs include atelectasis, pneumonia, respiratory failure, pulmonary embolism, and worsening chronic lung disease. Surgical urgency, type, duration, approach of the surgical procedure, and comorbidities influence PPC rates, with cardiac, thoracic, abdominal, and vascular surgeries being particularly vulnerable.

Patient-related risk factors encompass non-pulmonary and pulmonary factors. Aging populations increase surgical demand, with advanced age and frailty predicting higher morbidity and mortality risks. Conditions like congestive heart failure, obesity, obstructive sleep apnea, and smoking heighten PPC risks. Asthma, chronic obstructive pulmonary disease, interstitial lung diseases, pulmonary hypertension, previous pulmonary thromboembolism, acute respiratory infections, and COVID-19 impact pulmonary risk profiles. Surgery and anesthesia-related risk factors include the site of surgery, operation time, and emergency surgery. Surgery near the diaphragm elevates PPC risk, while longer operation times correlate with increased PPC incidence. Emergency surgeries pose challenges in risk assessment. Anesthetic techniques influence outcomes, with regional anesthesia often preferable. Neuromuscular blocking agents impact PPCs, and protective ventilation strategies can mitigate complications.

As current literature lacks a comprehensive approach to PPE, in this review, we present a comprehensive approach to preoperative pulmonary approach to surgical patients to help in risk stratification, further optimization, as well as shared decision making between the surgeon and the patients and their family prior to consenting for a major surgical procedure.

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