术前用铁或不用铁治疗贫血患者手术结果的差异

Francisco Javier García Sánchez, Almudena Nieto Ramos, Natalia Mudarra García
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引用次数: 0

摘要

目的:了解术前用羧麦芽糖铁(FCM)治疗与术前不加铁治疗贫血患者手术效果的差异。方法:对两组患者进行回顾性观察研究:术前无FCM组(实施手术前)和术前有FCM组(实施手术前)。电子临床记录综述结果变量为术后输血次数、术后并发症和住院天数。通过卡方检验和学生t检验对研究变量进行比较;使用SPSS统计程序,v. 26。结果:研究纳入152例患者,FCM组92例(2020-2022),非FCM组56例(2019);60.5% (n= 92)为女性。平均年龄(标准差)为63.91(13)岁。包括的手术包括:结肠切除术(n= 77;64.5%),乳房切除术(n= 55;23%)和子宫切除术(n= 20;12.5%)。有统计学意义的结果发现输血需求(p< 0.001;OR 15.91(4.44-57.01)),术后并发症(p< 0.001;OR为7.36(3.35-16.16)),平均住院时间(p< 0.001), FCM组为4.14天,对照组为9天。结论:FCM治疗减少了输血次数、术后并发症和住院天数。
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Diferencias en los resultados quirúrgicos en pacientes con anemia preoperatoria tratada con hierro o sin hierro previo a la cirugía
Objectives: to understand the differences in surgical results in patients with preoperative anemia treated with Ferric carboxymaltose (FCM) or without iron before surgery.Methods: a retrospective observational study of two patient cohorts: a Group without preoperative FCM (before the implementation of the Surgical Prehabilitation program), and a Group with FCM (after the implementation of the program). A review of electronic clinical records; the outcome variables were the number of transfusions of blood products required after surgery, postsurgical complications, and days of hospital stay. There was a comparison of study variables through Chi square and Student’s t tests; the SPSS statistical program, v. 26, was used.Results: the study included 152 patients, 92 in the FCM Group (2020-2022) and 56 in the Group without FCM (2019); 60.5% (n= 92) were female. Their mean age (standard deviation) was 63.91 (13) years. The surgical procedures included were: colectomy (n= 77; 64.5%), mastectomy (n= 55; 23%) and hysterectomy (n= 20; 12.5%). Statistically significant outcomes were found between the need for blood transfusions (p< 0.001; OR 15.91 (4.44-57.01)), postsurgical complications (p< 0.001; OR 7.36 (3.35-16.16)), and the mean hospital stay (p< 0.001), which was 4.14 days in the FCM group vs. nine days in the control group without FCM.Conclusions: treatment with FCM reduced the number of blood transfusions, postsurgical complications, and days of hospital stay.
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