肺癌术后患者负性情绪、生活质量与中医证候特征及相关分析:一项横断面研究

IF 4.3 3区 医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE World Journal of Traditional Chinese Medicine Pub Date : 2023-01-01 DOI:10.4103/2311-8571.385512
Ya-Bin Gong, Ling Xu, Cong-Meng Zhang, Yi-Feng Gu, Sheng-Ping Shen, Yi-Chao Wang, Ao Qi, Ling-Zi Su, Jia-Lin Yao, Jia-Qi Li, Wen-Xiao Yang, Qin Wang, Li-Jing Jiao, Xiong Qin
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引用次数: 0

摘要

目的:观察分析非小细胞肺癌(NSCLC)患者术后1 ~ 3个月的负性情绪及生活质量(QoL)特征,总结其术后人群特征。材料与方法:术后1 ~ 3个月为巩固康复期。主要观察指标为综合医院焦虑抑郁量表、欧洲癌症研究与治疗组织核心生活质量问卷(EORTC QLQ-C30)、EORTC QLQ-Lung Cancer-13。次要观察指标为外周血细胞因子和免疫功能指标。采用单因素方差分析、logistic回归等统计方法分析这部分人群的特征。结果:在肺部手术患者中,焦虑在巩固恢复期间的总体发生率为13.66%,抑郁为10.38%。疲劳、疼痛、呼吸困难、失眠、食欲减退评分明显高于其他症状(P = 0.000)。焦虑的存在与手术部位相关(P < 0.05),抑郁的存在与情绪功能和呼吸困难相关(P < 0.05)。结论:NSCLC术后人群负性情绪的发生与性别有关,且负性情绪程度与生活质量呈负相关,与症状程度呈正相关。相关的证候主要有肺证和经证。
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Characteristics and correlation analysis of negative emotions, quality of life, and chinese medicine syndromes in patients with lung cancer after surgery: A cross-sectional study
Objective: The objective of the study was to observe and analyze the characteristics of negative emotions and quality of life (QoL) in patients with nonsmall cell lung cancer (NSCLC) from 1 to 3 months after surgery, and summarize their population characteristics after surgery. Materials and Methods: The consolidation rehabilitation period was defined as 1 to 3 months after surgery. The main observation indicators were the general Hospital Anxiety and Depression Scale, the European Organization for the Research and Treatment of Cancer Core QoL Questionnaire (EORTC QLQ-C30), and EORTC QLQ-Lung Cancer-13. The secondary observation indicators were peripheral blood cytokines and immune function indicators. Statistical methods such as one-way analysis of variance and logistic regression were used to analyze the characteristics of this part of the population. Results: Among patients who underwent lung surgery, the overall incidence of anxiety during consolidation recovery was 13.66%, and that of depression was 10.38%. The scores of fatigue, pain, dyspnea, insomnia, and loss of appetite were significantly higher than those of other symptoms (P = 0.000). The presence of anxiety was associated with the site of surgery (P < 0.05) and the presence of depression was associated with emotional functioning and dyspnea (P < 0.05). Conclusions: The occurrence of negative emotions in the postoperative NSCLC population is related to gender, and the degree of emotions is negatively correlated with QoL and positively correlated with the degree of symptoms. The main relevant syndromes are the pulmonary and meridian categories.
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来源期刊
World Journal of Traditional Chinese Medicine
World Journal of Traditional Chinese Medicine Medicine-Complementary and Alternative Medicine
CiteScore
5.40
自引率
2.30%
发文量
259
审稿时长
24 weeks
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