假马齿苋(Bacopa monnieri)植物成分及抗菌特性分析抗临床病原体

N. Amudha, R. Magalingam, K. Selvam, V. Ambikapathy, P. Prakash
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引用次数: 0

摘要

药用植物在治疗和管理许多疾病方面有许多治疗用途。在目前的情况下,最需要的是传统的药用植物。世界上温暖的湿地地区是假马齿苋(L.)的故乡。它已经在阿育吠陀系统中使用了很长时间。假马齿苋是我国传统的药用植物之一。这些通常被称为“婆罗门”,泰米尔方言的名字是“Neerbrahmmi”。一年四季都易于栽培和生长。这些特殊的活性成分,也被称为记忆增强和植物成分丰富的药用植物。本研究主要对假马齿苋叶片的植物成分及其抑菌活性进行了分析。在不同极性溶剂和非极性溶剂下,研究了植物成分对最小抑菌浓度的抑菌活性。分别记录了生物碱、氨基酸、香豆素、黄酮类、苷类、酚类、酞菁、醌类、还原糖、皂苷、甾体、单宁、萜类等植物成分。测定了对丁酸梭菌、大肠杆菌、金黄色葡萄球菌、肺炎链球菌等人类临床细菌的抑菌活性,以及对黄曲霉、黑曲霉、曲霉、青霉等人类临床细菌的抑菌活性。在两种溶剂萃取中,水萃取比苯萃取效果更显著。根据MIC对不同提取物的抑菌性能进行了分析。极低的浓度显示出对微生物更好的抑制作用。本研究探讨了人类临床病原菌的抗菌特性。因此,建议用山茱萸叶提取物治疗微生物感染。
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Analysis of Phytoconstituents and Antimicrobial Properties of Bacopa monnieri (L.) Against Clinical Pathogen
There are numerous therapeutic uses for medicinal plants in treating and managing numerous diseases. Traditional medicinal plantswere mostly needed in the current scenario. The world's warmer and wetlands regions are home to the medicinal herb Bacopa monnieri (L.).It has been utilized for ages in Ayurvedic systems. The Bacopa monnieri was one of the traditional medicinal plants. These are commonlycalled "Brahmi," and the Tamil vernacular name is "Neerbrahmmi." It is easy to cultivate and grow in all seasons. These peculiar activeingredients, also known as memory enhancement and phytoconstituents were enriched in this medicinal plant. The present study focused onanalyzing phytoconstituents and the antimicrobial activity of Bacopa monnieri leaves. The efficacy of phytoconstituents on the antimicrobialactivities concerning minimum inhibitory concentrations was performed with different polar and non-polar solvents of the respective plant.The phytoconstituents such as alkaloids, amino acids, coumarins, flavonoids, glycosides, phenols, phlobatannins, quinones, reducing sugars,saponins, steroids, tannins, and terpenoids were recorded, respectively. Antibacterial activity performed with following human clinicalbacteria like Clostridium butyricum, Escherichia coli, Staphylococcus aureus, and Streptococcus pneumoniae, and the antifungal activity against humanclinical such as Aspergillus flavus, A.niger, Aspergillus sp., and Penicillium sp. were determined. Among the two solvent extractions, the aqueousextract showed a more significant result than the benzene extract. According to the MIC, the antimicrobial properties of B.monnieriwithdifferent extracts were analyzed. The very minimum concentration has shown better inhibitions against microbes. The present study exploredthe antimicrobial properties of human clinical pathogens. So, the B.monnieriaqueous extract of leaves was suggested for the treatment ofmicrobial infections.
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