常用柑橘类植物绿色合成金纳米缀合物及其体外抗菌金黄色葡萄球菌的比较研究

Sudeshna Sengupta, Moumita Saha, Nishan Ranjan Ghosh, Malavika Bhattacharya, Sirshendu Chatterjee
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摘要

纳米技术属于现代科学的一个领域,在医学研究领域显示出许多积极的发展,主要涉及1-100纳米之间的颗粒尺寸。在众多制备金属纳米粒子的方法中,绿色制备金属纳米粒子的方法具有危害小、环保、经济等优点。根据各种文献研究,柑橘属植物作为富含抗癌和抗氧化物质的食物具有巨大的潜力。因此,本课题主要研究柑橘类植物(柠檬、柚子和香王柠檬)介导的金属纳米粒子的合成,并对其进行表征,确定其对金黄色葡萄球菌的抑菌性能。物理表征结果表明,柑橘介导的三种纳米粒子均在520 ~ 530 nm范围内呈现紫外可见光谱。生成的颗粒尺寸在1- 10nm之间。根据FTIR分析,在生产的纳米颗粒中存在几个官能团。柠檬香气王的体外抗氧化作用最大。这一总体结果支持柑橘类植物固有的抗氧化特性,这可能进一步支持其纳米颗粒合成的还原特性。
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Green synthesis of gold nano-conjugates using commonly used citrus species and evaluation of its In-vitro antibacterial efficacy against Staphylococcus aureus: A comparative study
Nanotechnology belongs to one of the areas of modern science, demonstrated numerous positive developments in the realm of medical research, basically deals with the particle size ranging between 1-100 nm. Out of so many methods for developing the metal nanoparticles, the green approach for metal nanoparticles preparation is less hazardous, eco-friendly and cost effective. According to various literature studies, plants belonging to Citrus species have enormous potential as anticancer and antioxidant rich food items. Therefore our present research work aims at the Citrus species (lemon, pummelo and the aroma king lemon) mediated Metal nano-particle synthesis followed by their characterization and determining its antibacterial property of against Staphylococcus aureus bacterium. According to the results of physical characterizations, all the three Citrus mediated nanoparticles show UV-Vis spectra within 520-530 nm. And have the particle size generated within 1-10 nm. Several functional groups are present in the produced nanoparticles, according to an FTIR analysis. The in-vitro antioxidant efficacy was maximum shown by the aroma king lemon. This overall results supports the innate antioxidant properties of Citrus species plants that may further supports its reducing property for nanoparticle synthesis.
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