牛顿纳米流体在被热组织包围的垂直圆柱形容器上的数值研究

IF 2.8 Q2 MULTIDISCIPLINARY SCIENCES SN Applied Sciences Pub Date : 2023-11-07 DOI:10.1007/s42452-023-05527-0
R. S. Kamel, A. M. Ismaeel, F. M. Hady
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引用次数: 0

摘要

摘要:本文介绍了一个理论模型来研究磁场中生物组织的传热传质问题,该模型模拟了用热疗法治疗癌症的过程。特别是,该模型结合了布朗运动和纳米颗粒热泳动的影响。首先利用相似变换将非线性运动控制方程转化为常微分方程,然后利用MATLAB内置的求解器- bvp4c根据适当的边界条件进行数值求解。对各参数及其对流动的影响进行了研究。模型预测表明,增加纳米颗粒在组织中的吸热,可以提高肿瘤温度,从而提高治疗效率,降低纳米颗粒的浓度。因此,本研究结果可提高热疗对恶性肿瘤的疗效。当换热系数提高时,纳米颗粒向深层组织的传递加快。间隙液的温度显著降低了间隙液的速度。将肿瘤暴露于外部热源可以增强NP对肿瘤的递送。
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Numerical study for a newtonian nanofluid over a vertical cylindrical vessel surrounded by a hot tissue
Abstract This manuscript introduces a theoretical model to study the problem of heat and mass transfer in biological tissues in a magnetic field, which simulates cancer treatment using thermal therapy. In particular, this model incorporates the influence of the Brownian motion and thermal thermophoresis of nanoparticles. Firstly, the non-linear governing equations of motion are transformed into ordinary differential equations using similarity transformations, then solved numerically according to appropriate boundary conditions using MATLAB built-in solver- bvp4c. All parameters and their impacts on the flow have been investigated and studied. The model predictions showed that increasing the heat absorption by nanoparticles in the tissue increases the tumour temperature, which helps to improve the therapeutic efficiency and reduce the concentration of nanoparticles. Hence, the results of this study could enhance the effectiveness of thermal therapy for malignancies. Article Highlights The transport of nanoparticles (NPs) to the deep tissue is improved when the heat transfer coefficient is raised. The temperature of interstitial fluid significantly reduces the velocity of the interstitial fluid. Exposing tumours to an external heat source enhances the NP delivery to the tumour.
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来源期刊
SN Applied Sciences
SN Applied Sciences MULTIDISCIPLINARY SCIENCES-
自引率
3.80%
发文量
292
审稿时长
22 weeks
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