挤压细胞学诊断额骨浆细胞瘤为非分泌性多发性骨髓瘤的首发表现

Vaishali B. Nagose, Swapnil B. Patil, Neha A. Mahajan
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摘要

摘要骨浆细胞瘤是浆细胞骨髓瘤(多发性骨髓瘤)的诊断标准之一。浆细胞瘤累及额骨是不寻常的,迄今仅有少数报道。此外,当没有典型的临床表现时,通常不怀疑临床放射学诊断。我们报告一例罕见的额骨浆细胞瘤,表现为额头上的肿块,其挤压细胞学诊断为肿瘤病因。因此,壁球细胞学有助于该患者的早期和明确诊断,加快细致的诊断调查和适当的管理。经过全面检查,最终诊断为非分泌性多发性骨髓瘤。
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Squash Cytology Diagnosing Plasmacytoma of Frontal Bone as First Presentation of Nonsecretory Multiple Myeloma
Abstract Plasmacytoma of bone is one of the criteria for diagnosing plasma cell myeloma (multiple myeloma). A plasmacytoma involving a frontal bone is unusual, with only few being reported so far. Also, when typical clinical presentation is absent, diagnosis is usually not suspected clinicoradiologically. We report a rare case of frontal bone plasmacytoma presenting as a lump over the forehead, the squash cytology of which gave the diagnosis of neoplastic etiology. Thus, squash cytology helped in early and definitive diagnosis in this patient, hastening meticulous diagnostic investigations and appropriate management. With full workup, the final diagnosis of a nonsecretory multiple myeloma was made.
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