神经外科地塞米松治疗患者实验室静脉血血糖与血糖仪测毛细血管血糖的相关性研究

Jyoti Sharma, Renu Bala, Seema Singh
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引用次数: 0

摘要

背景神经外科患者由于多种因素的影响,大脑容易出现极端血糖水平;围手术期使用地塞米松是最常见的。因此,建议经常监测血糖水平。本研究旨在探讨实验室法测得的静脉血糖与血糖仪测得的毛细血管血糖在不同时间间隔的相关性。材料与方法本前瞻性观察性研究纳入20例计划行脑肿瘤切除术的成年患者,男女皆可,美国麻醉医师学会分级为I至III级。已接受地塞米松治疗且术中接受8 mg地塞米松治疗的患者入组。所有患者均采用标准麻醉技术及术中监护。取静脉标本,实验室测血糖,同时用血糖仪测定毛细血管血糖。取样于基线,地塞米松给药后1小时至4小时,然后是8、12和24小时。评估两个值之间的相关性。结果分析了160例静脉血糖和160例毛细血管血糖。虽然毛细血管血糖水平略高于静脉血糖水平,但除24 h时两值不相关外,两者之间存在较强的相关性(Pearson相关系数),p值均小于0.05。结论血糖仪测得的毛细血管血糖水平与静脉血糖水平具有良好的相关性;因此,该方法可靠、简便、实用,可常规用于频繁血糖检测。
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Correlation of Venous Blood Sugar Measured by Lab Method and Capillary Blood Sugar Measured by Glucometer in Neurosurgical Patients Receiving Dexamethasone
Abstract Background Brain is vulnerable to extreme blood glucose levels that may occur due to multiple factors in neurosurgical patients; perioperative use of dexamethasone is the most common. Thus, frequent monitoring of blood sugar levels is advocated. This study aimed to assess correlation between venous blood sugar measured by lab method and capillary blood sugar by glucometer at various time intervals. Materials and Methods This prospective and observational study was conducted in 20 adult patients of either sex, American Society of Anesthesiologists grade I to III, scheduled to undergo brain tumor resection. The patients who were already on dexamethasone and received intraoperatively 8 mg dexamethasone were enrolled. Standard anesthesia technique and intraoperative monitoring were followed in all patients. Venous sample was withdrawn and blood sugar analyzed in laboratory, while at the same time capillary blood sugar was tested by glucometer. The sampling was done at baseline, 1 hourly after dexamethasone administration till 4 hours and then 8, 12, and 24 hours. The correlation between the two values was assessed. Results During the study, 160 venous and 160 capillary blood sugar levels were analyzed. Though capillary blood sugar levels were slightly higher than venous sugar levels, there was strong correlation between the two (Pearson correlation coefficient) with p-value less than 0.05 except at 24 hours when two values were not correlated. Conclusion Capillary blood sugar levels by glucometer have good correlation with venous sugar levels; therefore, this method may be adopted routinely for frequent blood sugar estimation as it is reliable, easy, and practical.
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