{"title":"神经内镜下血肿清除术治疗慢性硬膜下血肿的疗效及对患者神经功能的影响分析","authors":"Chun Dong, Jun Jia, Wei Meng","doi":"10.26689/cnr.v1i2.5284","DOIUrl":null,"url":null,"abstract":"Objective: To analyze the effect of neuroendoscopic hematoma evacuation on neurological function in patients with chronic subdural hematoma (CSDH). Methods: From September 2019 to September 2022, 113 patients with CSDH were selected and randomly divided into group A for neuroendoscopic hematoma evacuation and group B for soft channel drainage. The differences in neurological function of these two groups were compared. Results: Except for intraoperative blood loss and duration of surgery, all surgical indicators in group A were better than those in group B , P < 0.05. One month after operation, the neurological deficit (CSS) score in group A was lower than that in group B, and the quality of life (SF-36), activities of daily living (ADL) scores were higher than those in group B, with P < 0.05. 7 days after operation, the scores of superoxide dismutase (SOD), malondialdehyde (MDA), glutathione peroxidase (GSH-Px) and other oxidative stress indicators were better than those in group B, P < 0.05; the complication rate in group A was lower than that in group B, with P < 0.05. Conclusion: Neuroendoscopic hematoma evacuation therapy can regulate oxidative stress indicators, improve nerve defects, and improve the outcome of CSDH patients.","PeriodicalId":87465,"journal":{"name":"Clinical neuroscience research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Analysis of the Efficacy of Neuroendoscopic Hematoma Evacuation in the Treatment of Chronic Subdural Hematoma and its Influence on the Neurological Function of Patients\",\"authors\":\"Chun Dong, Jun Jia, Wei Meng\",\"doi\":\"10.26689/cnr.v1i2.5284\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: To analyze the effect of neuroendoscopic hematoma evacuation on neurological function in patients with chronic subdural hematoma (CSDH). Methods: From September 2019 to September 2022, 113 patients with CSDH were selected and randomly divided into group A for neuroendoscopic hematoma evacuation and group B for soft channel drainage. The differences in neurological function of these two groups were compared. Results: Except for intraoperative blood loss and duration of surgery, all surgical indicators in group A were better than those in group B , P < 0.05. One month after operation, the neurological deficit (CSS) score in group A was lower than that in group B, and the quality of life (SF-36), activities of daily living (ADL) scores were higher than those in group B, with P < 0.05. 7 days after operation, the scores of superoxide dismutase (SOD), malondialdehyde (MDA), glutathione peroxidase (GSH-Px) and other oxidative stress indicators were better than those in group B, P < 0.05; the complication rate in group A was lower than that in group B, with P < 0.05. Conclusion: Neuroendoscopic hematoma evacuation therapy can regulate oxidative stress indicators, improve nerve defects, and improve the outcome of CSDH patients.\",\"PeriodicalId\":87465,\"journal\":{\"name\":\"Clinical neuroscience research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical neuroscience research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.26689/cnr.v1i2.5284\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical neuroscience research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26689/cnr.v1i2.5284","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Analysis of the Efficacy of Neuroendoscopic Hematoma Evacuation in the Treatment of Chronic Subdural Hematoma and its Influence on the Neurological Function of Patients
Objective: To analyze the effect of neuroendoscopic hematoma evacuation on neurological function in patients with chronic subdural hematoma (CSDH). Methods: From September 2019 to September 2022, 113 patients with CSDH were selected and randomly divided into group A for neuroendoscopic hematoma evacuation and group B for soft channel drainage. The differences in neurological function of these two groups were compared. Results: Except for intraoperative blood loss and duration of surgery, all surgical indicators in group A were better than those in group B , P < 0.05. One month after operation, the neurological deficit (CSS) score in group A was lower than that in group B, and the quality of life (SF-36), activities of daily living (ADL) scores were higher than those in group B, with P < 0.05. 7 days after operation, the scores of superoxide dismutase (SOD), malondialdehyde (MDA), glutathione peroxidase (GSH-Px) and other oxidative stress indicators were better than those in group B, P < 0.05; the complication rate in group A was lower than that in group B, with P < 0.05. Conclusion: Neuroendoscopic hematoma evacuation therapy can regulate oxidative stress indicators, improve nerve defects, and improve the outcome of CSDH patients.