粘膜类天疱疮

Margaret DiRuggiero, Douglas DiRuggiero, Peter A. Young, Robert Page, Jane Clark, Emily Hall, John Chung
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引用次数: 0

摘要

摘要:有单独的病例报告描述了线性免疫球蛋白A (IgA)大疱性皮肤病,其组织学酷似口腔扁平苔藓,并累及眼部,导致失明。在这里,我们描述了一个病人与已知的眼部瘢痕疾病,但没有意识到口腔黏膜的发展皮疹。随后进行活组织检查,以调查线性IgA皮肤病是否表现出类似扁平地衣的地衣样变化,或者患者是否同时患有线性IgA皮肤病和扁平地衣。总之,这两种实体都可能引起疤痕,为了避免诊断混淆,我们将这两种实体都归类为粘膜类天疱疮。
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Mucous Membrane Pemphigoid
ABSTRACT: Separate case reports have described linear Immunoglobulin A (IgA) bullous dermatosis with histology mimicking oral lichen planus and ocular involvement with resultant blindness. Here, we describe a patient with known ocular cicatrizing disease but was unaware of an evolving rash of the oral mucosa. Subsequent biopsies were procured to investigate whether linear IgA dermatosis exhibited lichenoid changes mimicking lichen planus or if the patient had concomitant linear IgA dermatosis and lichen planus. Conclusively, both entities may cause scarring, and for the purpose of avoiding diagnostic confusion, we have categorically appropriated both under mucous membrane pemphigoid.
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来源期刊
CiteScore
0.30
自引率
25.00%
发文量
45
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