Larissa Lea da Silva, Marcelo Dutra Duque, Michele Georges Issa, Leticia Norma Carpentieri Rodrigues
{"title":"硝酸异山梨酯口腔崩解膜环糊精/HPMC:机械、光学和物理化学研究","authors":"Larissa Lea da Silva, Marcelo Dutra Duque, Michele Georges Issa, Leticia Norma Carpentieri Rodrigues","doi":"10.1590/1678-4324-2023220370","DOIUrl":null,"url":null,"abstract":"HIGHLIGHTS Orally films Cyclodextrins/HPMC based films were prepared by solvent casting. Films for oral delivery of ISDN were prepared by 32 factorial designs. Mechanical, optical, and dissolution properties were evaluated. The experimental design allowed to optimize the formulations. The best formulation was obtained by means of the desirability function.","PeriodicalId":9169,"journal":{"name":"Brazilian Archives of Biology and Technology","volume":"45 1","pages":"0"},"PeriodicalIF":1.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Isosorbide Dinitrate Orally Disintegrating Films Cyclodextrins/HPMC Based: Mechanical, Optical, and Physicochemical Studies\",\"authors\":\"Larissa Lea da Silva, Marcelo Dutra Duque, Michele Georges Issa, Leticia Norma Carpentieri Rodrigues\",\"doi\":\"10.1590/1678-4324-2023220370\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"HIGHLIGHTS Orally films Cyclodextrins/HPMC based films were prepared by solvent casting. Films for oral delivery of ISDN were prepared by 32 factorial designs. Mechanical, optical, and dissolution properties were evaluated. The experimental design allowed to optimize the formulations. The best formulation was obtained by means of the desirability function.\",\"PeriodicalId\":9169,\"journal\":{\"name\":\"Brazilian Archives of Biology and Technology\",\"volume\":\"45 1\",\"pages\":\"0\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Brazilian Archives of Biology and Technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1590/1678-4324-2023220370\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brazilian Archives of Biology and Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1590/1678-4324-2023220370","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOLOGY","Score":null,"Total":0}
Isosorbide Dinitrate Orally Disintegrating Films Cyclodextrins/HPMC Based: Mechanical, Optical, and Physicochemical Studies
HIGHLIGHTS Orally films Cyclodextrins/HPMC based films were prepared by solvent casting. Films for oral delivery of ISDN were prepared by 32 factorial designs. Mechanical, optical, and dissolution properties were evaluated. The experimental design allowed to optimize the formulations. The best formulation was obtained by means of the desirability function.
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