一对夫妇曾多次尝试通过卵-积云复合体选择精子,但没有成功,他们生下了一个健康的孩子。病例报告

Q3 Medicine Gynecology Pub Date : 2023-10-04 DOI:10.26442/20795696.2023.3.202115
Alina V. Chistyakova, Alina A. Babayan, Alina А. Dovgan, Natalya P. Makarova, Natalya N. Lobanova, Veronika Yu. Smolnikova
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引用次数: 0

摘要

在男性不育症中,夫妇必须使用辅助生殖技术与卵胞浆内单精子注射(ICSI)技术。ICSI的一个显著缺点是绕过了自然选择障碍,因为女性生殖道的选择过程被基于精子活力和形态标准的胚胎学家的选择所取代。人们正在积极研究各种选择方法,使ICSI受精更接近生理,确保选择DNA质量高、受精潜力好的精子。本文介绍了一对患有严重男性不育症的已婚夫妇生下一个健康孩子的临床病例,并多次尝试使用卵母细胞-积云复合体的精子选择方法进行辅助生殖技术。这孩子身体健康,随年龄发展。
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The birth of a healthy child in a married couple with a history of multiple unsuccessful attempts at ART by selecting sperm on oocyte-cumulus complexes. Case report
In male infertility, couples must use assisted reproductive technologies with the intracytoplasmic sperm injection (ICSI) technique. A significant disadvantage of ICSI is bypassing natural selection barriers since selective processes in the female reproductive tract are replaced by the choice of an embryologist based on sperm motility and morphological criteria. Various selection methods are being actively studied, bringing fertilization by ICSI closer to physiological, ensuring the selection of sperm with high DNA quality and good potential for fertilization. The article presents a clinical case of the birth of a healthy child in a married couple with severe male infertility and many ineffective attempts at assisted reproductive technologies using the method of sperm selection on oocyte-cumulus complexes. The child is physically healthy and develops according to age.
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来源期刊
Gynecology
Gynecology Medicine-Obstetrics and Gynecology
CiteScore
0.70
自引率
0.00%
发文量
52
审稿时长
8 weeks
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