不同合并症的COVID - like疾病(CLI)患者疑似不良事件的分布和决定因素

Shahana Sarwar, Muhammad Tanvir Mohith, Muhammad Marnush, Muhammad Nafees Hussain, Md Sayedur Rahman Rahman, Tahmina Begum
{"title":"不同合并症的COVID - like疾病(CLI)患者疑似不良事件的分布和决定因素","authors":"Shahana Sarwar, Muhammad Tanvir Mohith, Muhammad Marnush, Muhammad Nafees Hussain, Md Sayedur Rahman Rahman, Tahmina Begum","doi":"10.3329/jninb.v9i1.65382","DOIUrl":null,"url":null,"abstract":"Background: Several drugs were administered to patients with COVID-19, focusing on their antiviral, immunomodulatory, or anti-inflammatory actions, which could potentially present risk since most of these medicines have the potential to cause numerous adverse effects. Objective: This study aimed to observe the incidence of suspected adverse events of selected medicines among COVID-like ill (CLI) patients. Methodology: A prospective analysis was performed from February 15, 2021, to June 15, 2021, upon 223 CLI patients. CLI patients were enrolled from the National Institute of Diseases of the Chest and Hospital. The incidence of suspected adverse events were assessed among CLI patients, the laboratory investigations values of SGPT, RBS, serum electrolytes, and serum creatinine of day one and day five and interpreted the 12-lead ECG tracing paper of the same days assessed hepatotoxicity, nephrotoxicity, cardiotoxicity, and metabolic disorders. Results: The result showed the incidence of adverse events was 21.5% in CLI patients. Only the incidence of hepatotoxicity was more (12.55%) among CLI patients but statistically not significant (p > 0.05). In CLI patients who had co-morbidities, the incidence of adverse events was relatively less and only a significant difference was seen among diabetes mellitus patients (p ≤ 0.05). Conclusion: This study showed that the rate of adverse events was present in CLI patients when treated with the same specific drug of interest in addition to other medicines they received. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):35-41","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"89 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Distribution and Determinants of Suspected Adverse Events among COVID like Illness (CLI) Patients with Different Comorbidities\",\"authors\":\"Shahana Sarwar, Muhammad Tanvir Mohith, Muhammad Marnush, Muhammad Nafees Hussain, Md Sayedur Rahman Rahman, Tahmina Begum\",\"doi\":\"10.3329/jninb.v9i1.65382\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Several drugs were administered to patients with COVID-19, focusing on their antiviral, immunomodulatory, or anti-inflammatory actions, which could potentially present risk since most of these medicines have the potential to cause numerous adverse effects. Objective: This study aimed to observe the incidence of suspected adverse events of selected medicines among COVID-like ill (CLI) patients. Methodology: A prospective analysis was performed from February 15, 2021, to June 15, 2021, upon 223 CLI patients. CLI patients were enrolled from the National Institute of Diseases of the Chest and Hospital. The incidence of suspected adverse events were assessed among CLI patients, the laboratory investigations values of SGPT, RBS, serum electrolytes, and serum creatinine of day one and day five and interpreted the 12-lead ECG tracing paper of the same days assessed hepatotoxicity, nephrotoxicity, cardiotoxicity, and metabolic disorders. Results: The result showed the incidence of adverse events was 21.5% in CLI patients. Only the incidence of hepatotoxicity was more (12.55%) among CLI patients but statistically not significant (p > 0.05). In CLI patients who had co-morbidities, the incidence of adverse events was relatively less and only a significant difference was seen among diabetes mellitus patients (p ≤ 0.05). Conclusion: This study showed that the rate of adverse events was present in CLI patients when treated with the same specific drug of interest in addition to other medicines they received. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):35-41\",\"PeriodicalId\":16732,\"journal\":{\"name\":\"Journal of National Institute of Neurosciences Bangladesh\",\"volume\":\"89 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-10-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of National Institute of Neurosciences Bangladesh\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3329/jninb.v9i1.65382\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of National Institute of Neurosciences Bangladesh","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3329/jninb.v9i1.65382","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

背景:对COVID-19患者使用了几种药物,重点是它们的抗病毒、免疫调节或抗炎作用,这可能存在风险,因为大多数这些药物都有可能引起许多不良反应。目的:观察新型冠状病毒病(CLI)患者选定药物疑似不良事件的发生率。方法:对223例CLI患者于2021年2月15日至2021年6月15日进行前瞻性分析。CLI患者来自国家胸病和医院研究所。评估CLI患者疑似不良事件的发生率,第1天和第5天SGPT、RBS、血清电解质、血清肌酐的实验室调查值,并解读当天12导联心电图示踪纸,评估肝毒性、肾毒性、心脏毒性和代谢紊乱。结果:CLI患者不良事件发生率为21.5%。仅肝毒性发生率高于CLI患者(12.55%),但差异无统计学意义(p >0.05)。合并合并症的CLI患者不良事件发生率相对较低,仅糖尿病患者不良事件发生率有显著性差异(p≤0.05)。结论:本研究表明,在接受其他药物治疗的同时,使用相同的特定药物治疗CLI患者的不良事件发生率是存在的。孟加拉国国家神经科学研究所杂志,2023年1月;9(1):35-41
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Distribution and Determinants of Suspected Adverse Events among COVID like Illness (CLI) Patients with Different Comorbidities
Background: Several drugs were administered to patients with COVID-19, focusing on their antiviral, immunomodulatory, or anti-inflammatory actions, which could potentially present risk since most of these medicines have the potential to cause numerous adverse effects. Objective: This study aimed to observe the incidence of suspected adverse events of selected medicines among COVID-like ill (CLI) patients. Methodology: A prospective analysis was performed from February 15, 2021, to June 15, 2021, upon 223 CLI patients. CLI patients were enrolled from the National Institute of Diseases of the Chest and Hospital. The incidence of suspected adverse events were assessed among CLI patients, the laboratory investigations values of SGPT, RBS, serum electrolytes, and serum creatinine of day one and day five and interpreted the 12-lead ECG tracing paper of the same days assessed hepatotoxicity, nephrotoxicity, cardiotoxicity, and metabolic disorders. Results: The result showed the incidence of adverse events was 21.5% in CLI patients. Only the incidence of hepatotoxicity was more (12.55%) among CLI patients but statistically not significant (p > 0.05). In CLI patients who had co-morbidities, the incidence of adverse events was relatively less and only a significant difference was seen among diabetes mellitus patients (p ≤ 0.05). Conclusion: This study showed that the rate of adverse events was present in CLI patients when treated with the same specific drug of interest in addition to other medicines they received. Journal of National Institute of Neurosciences Bangladesh, January 2023;9(1):35-41
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Behavior of Non-Hybrid and Hybrid Forms of Fibro-Osseous Lesions in the Cranio-Maxillofacial Region of Patients Attending at the Tertiary Care Hospital in Dhaka City of Bangladesh Association of Ischaemic Heart Disease with Hospitalized Ischaemic Stroke Patients in a Tertiary Care Hospital Trend of Patients Attended at Emergency Department of Referral Neurosciences Hospital in Bangladesh Rare Association between Congenital Dorsal Dermal Sinus with Tethered Cord Syndrome: A Case Report Subclavian Steal Syndrome Presented with Recurrent Syncope: A Case Report
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1