工作记忆、反刍和自传体记忆特异性损伤

Pouria Rahgosha, Pezhman Hadinezhad, Seyed Hamzeh Hosseini, Ehsan Abedini
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引用次数: 0

摘要

目的:特异性损伤是发生在重度抑郁症(MDD)患者中的一种记忆改变。在这项研究中,我们打算揭示执行资源和捕获和反刍框架的模糊方面,以确定这些理论在预测特异性损伤的潜在机制方面是否可靠。方法:在本次相关研究中,我们采用便利抽样方法,时间跨度为2021年1月至2月。本研究采用数字广度工作记忆测试、反刍反应量表(RRS)和自传式记忆访谈来研究工作记忆容量和反刍亚型是否能预测重度抑郁症患者的记忆特异性。使用RRS使我们能够确定反刍亚型与记忆特异性之间的相关性。结果:我们的样本包括105名成年MDD患者,其中男性53人(50.5%),女性52人(49.5%)。参与者的平均年龄为33.38岁,年龄范围为22-43岁。结果性别、婚姻、年龄对记忆特异性的影响差异无统计学意义(P>0.05)。Spearman相关系数和多元回归分析结果显示,只有工作记忆容量能预测记忆特异性(r=0.216, p<0.05)。作为反刍和记忆特异性的两种亚型,沉思和反思之间没有显著的相关性。讨论:根据我们的研究结果,应该指出抑郁症伴随着执行力缺陷,从而导致记忆障碍。这些损伤是由于抑郁症患者大脑结构和功能的改变。正如Carfax模型所强调的那样,工作记忆容量不仅需要维持、定义和保持最优检索模型,而且对抑制干扰自传体信息也至关重要。然而,无论是沉思还是反思都不能预测记忆的特异性。因此,内存容量的占用可能是由于无效的搜索策略,而不是反刍。
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Working Memory, Rumination, and Autobiographical Memory Specificity Impairment
Objectives: Specificity impairment is a memory alteration that occurs in people with major depressive disorder (MDD). In this investigation, we intended to shine a light on obscure aspects of executive resource and capture and rumination frameworks to determine whether these theories are reliable in predicting underlying mechanisms for specificity impairment. Methods: In this correlational research, we used the convenience sampling method over two months, between January and February 2021. We administrated the digit span working memory test, ruminative response scale (RRS), and autobiographical memory interview to indicate whether working memory capacity and subtypes of rumination can predict memory specificity in people with MDD. Using RRS enabled us to determine the correlation between subtypes of rumination and memory specificity. Results: Our samples consisted of 105 adults (53 males (50.5%) and 52 females (49.5%)) with MDD. The participants’ mean age was 33.38 years with a range of 22-43 years. The results no significant difference between gender, marriage, and age groups in terms of memory specificity (P>0.05). The results of the Spearman correlation coefficient and multiple regression analysis showed that only working memory capacity can predict memory specificity (r=0.216, p<0.05). There was no significant correlation between brooding and reflection, as two subtypes of rumination and memory specificity. Discussion: In line with our results, it should be stated that depression is accompanied by executive deficits, which result in memory impairments. These impairments are due to the structural and functional alterations in the brain in the depressed group. As the Carfax model emphasized, working memory capacity is not only required to maintain, define, and hold the optimal retrieval model but it is also crucial to inhibit interfering autobiographical information. Nonetheless, neither brooding nor reflection rumination can predict memory specificity. Therefore, memory capacity is probably occupied due to ineffective search strategies, not rumination.
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来源期刊
Iranian Rehabilitation Journal
Iranian Rehabilitation Journal Medicine-Rehabilitation
CiteScore
0.60
自引率
0.00%
发文量
12
审稿时长
6 weeks
期刊介绍: Iranian Rehabilitation Journal aims to provide the readers with a variety of topics, including: original articles, hypothesis formation, editorials, literature reviews, case reports, short communications, special reports, letters to the editor, discussions of public policy issues and book reviews, and methodology articles in the fields of rehabilitation and social welfare, including (but not limited to): -Clinical and basic research in various special needs groups -Physical and mental rehabilitation -Epidemiological studies on disabling conditions -Biostatistics -Vocational and socio-medical aspects of rehabilitation IRJ also welcomes papers focusing on the genetic basis of common disabling disorders across human populations. Those studies may include (but not limited to): -The genetic basis of common single gene and complex disorders. -Bioinformatics tools to investigate and to model biological phenomena -Novel computational tools and databases -Sequence analysis -Population analysis -Databases and text mining
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