简化评分系统以预测北印度某三级护理教学医院急诊科收治的儿科患者的预后

Anita Kumari, Prakhar Gupta, Ruchika Bhatnagar, Kanika Aggarwal, None Ruby
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摘要

背景:估计急诊科(ED)的发病率和死亡率只能使儿科医生评估患者的预后并制定相应的治疗计划。本研究旨在开发和验证一个简单的评分系统,并建立临床参数与患者预后之间的相关性。对象和方法:记录入院时体温、呼吸频率、心率、血压(BP)、脉搏血氧饱和度(SpO2)、毛细血管再充血时间、感觉水平、癫痫发作情况和随机血糖水平等9项参数。如果参数是正常的,则赋值为“0”。上述参数的异常以1到3分的分数表示。主要结局以死亡/生存来评估。结果:57.2%的患者需要重症监护,14.75%的患者死亡。单因素分析显示,7个临床参数与死亡率显著相关。在多因素logistic回归分析中,血压、SpO2和体温异常是死亡率的独立预测因子(P < 0.05)。受试者工作特征为0.798(95%置信区间0.755-0.836;P < 0.0001)对死亡结局的预测能力(评分预测能力为79.8%)。1-5分、6-10分和>10分患者的死亡率分别高出4.923、23.143和112.0分。结论:该评分系统预测急诊科患儿病情严重程度和预后的敏感性为71.19%,特异性为72.14%。评分越高,患儿预后越差。
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Simplified scoring system to predict outcome in pediatric patients admitted through emergency department from a tertiary care teaching hospital of North India
Background: Estimating the morbidity and mortality in the emergency department (ED) only allows the pediatricians to assess the prognosis of the patient and plan therapies accordingly. This study was conducted to develop and validate a simple scoring system and establish a correlation between clinical parameters and the outcome of the patient. Subjects and Methods: Nine parameters, i.e., body temperature, respiratory rate, heart rate, blood pressure (BP), pulse oxygen saturation (SpO2), capillary refill time, level of sensorium, presence of seizure, and random blood sugar level, were documented, at the time of admission. Parameters were assigned a score of “0” if it is normal. An abnormality in the above parameters were indicated by a score ranging from 1 to 3. The primary outcome was assessed in terms of death/survival. Results: Out of the total, 57.2% required critical care, and mortality was reported in 14.75% of cases. On univariate analysis, seven clinical parameters were significantly associated with mortality. In multivariate logistic regression analysis, abnormalities in BP, SpO2, and temperature were independent predictors of mortality (P < 0.05). The receiver operating characteristic was 0.798 (95% confidence interval, 0.755–0.836; P < 0.0001) for the outcome of mortality (the predictive ability of score of 79.8%). The patients with scores 1–5, 6–10, and >10 had 4.923, 23.143, and 112.0 higher odds of mortality, respectively. Conclusions: This scoring system predicts the severity of illness and outcome with a sensitivity of 71.19% and specificity of 72.14%, respectively, in the ED. Higher scores predict unfavorable outcomes in these children.
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