在苏凡草药研究中心进行了与呼吸道感染相关的细菌筛选和姜蒜茶提取物的协同作用

Khalid Ibrahim Yahaya, Musbahu Abdullahi Abubakar, Muhyiddin Muhd Haruna, Musbahu Sani Abubakar
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引用次数: 0

摘要

呼吸道感染是人类最常见的传染病,其传播方式普遍,给公共卫生带来沉重负担。本研究旨在分离与呼吸道感染相关的病原菌,并利用协同效应评价潜在分离株姜蒜茶提取物的抑菌活性。本研究发现,从痰和咽拭子采集的200份样本中存在41株呼吸道病原体。经培养和生化鉴定分离鉴定目标病原菌,分别阳性7例(17.07%)、16例(39.02%)、14例(34.15%)、3例(07.39%)和1例(02.44%)。在大蒜姜茶醇提物与乙醇提物的协同抑菌作用方面,本研究分离得到的呼吸道病原菌除乙醇在150mg/ml时活性最高,为17±0.7mm外,其余均表现出较强的抑菌作用,乙醇在100mg/ml时活性最高,为15±0.2 mm。在50mg/ml时,两者的活性最低为07±0.2mm。
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Bacterial screening associated with respiratory infection and the synergistic effect of ginger and garlic tea extract conducted at assulfan herbal research center
Respiratory tract infection are the most common infectious diseases in human due to its common mode of transmission and leading a heavy burden to Public Health. The study was aimed to isolate the bacterial pathogens that are associated with respiratory infection and using synergistic effect to evaluate the antibacterial activity of ginger and garlic tea extract of potential isolates. The present study revealed the presence of 41 isolates of respiratory pathogens out of 200 Sample collected from sputum and swab throat. The isolation and identification of target pathogens were done using Cultural and biochemical Characterizations. 7(17.07%), 16(39.02%), 14(34.15%), 3(07.39%) and 1(02.44%) are positive of respectively. For the synergistic antibacterial effect of both methanolic and ethanolic extracts of garlic and ginger tea, all respiratory pathogens that were isolated in the present study were showed the great antibacterial effect except has highest activity of 17±0.7mm at 150mg/ml in methanolic while in ethanolic with 15±0.2 at 100mg/ml. Lowest activity was found to be 07±0.2mm at 50mg/ml for both and .
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