喀拉拉邦南部三级保健中心支气管扩张患者的临床、放射学和微生物学概况

Stephen Sunny, Mathew Ninan
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摘要

支气管扩张是一种常见但被忽视的慢性肺部疾病。印度南部缺乏关于支气管扩张患者的临床、放射学和微生物学资料。研究喀拉拉邦南部一家三级保健中心支气管扩张患者的临床特征、放射学模式和微生物菌群。对41例患者进行了为期一年的描述性横断面研究。本研究共纳入41例患者,其中男性18例(44%),女性23例(56.1%),主要年龄在61-70岁之间(51.2%)。大多数为非吸烟者(65%,N=27)。最常见的原因是结核后支气管扩张(34%,N=14)。主要症状为咳嗽(73.2%,N=30)和咳痰(70.7%,N=29),主要临床症状为咯噔(73.1%,N=30)。PFT以梗阻为主(60.97%,N=25),其中重度梗阻占48% (N=12)。影像学上,最常见的CT表现为囊性支气管扩张(46.3%,N=19),主要位于下肺叶(63.4%,N=26),累及双侧(65.9%,N=27)。最常见的分离菌为(43.9%,N=18),其次为(29.3,N=12)。大多数患者为女性,结核后支气管扩张是支气管扩张的主要原因。咳嗽和咳痰是最常见的症状。是痰样本中最常见的病原体。肺活量测定显示大多数患者为阻塞性,最常见的影像学表现为囊性支气管扩张。
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Clinical, radiological and microbiological profile of patients with bronchiectasis in a tertiary care center in South Kerala
Bronchiectasis is a common but neglected chronic lung disease. There is paucity of data from Southern India regarding the clinical, radiological and microbiological profile of patients with bronchiectasis. To study the clinical profile, radiological pattern and microbiological flora in patients with bronchiectasis in a tertiary care center in South Kerala. A descriptive cross-sectional study done in 41 patients over 1 year. This study comprised 41 patients, of whom 18 were males (44%) and 23 were females (56.1 %), with a predominant population pertaining to 61-70 years (51.2%). Majority were non-smokers (65%, N=27). Most common cause was post-TB bronchiectasis (34%, N=14). Predominant symptoms were cough (73.2%, N=30) and sputum production (70.7%, N=29), predominant clinical sign was crepitation (73.1%, N=30). Majority had PFT showing obstruction (60.97%, N=25), among which 48% (N=12) had severe obstruction. Radiologically, most common CT pattern was cystic bronchiectasis (46.3%, N=19), predominantly located in lower lobes (63.4%, N=26) with bilateral involvement (65.9%, N=27). was the most frequently isolated organism (43.9%, N=18) followed by (29.3, N=12). Most of our patients were females and post TB bronchiectasis was the leading cause of bronchiectasis. Cough and sputum production were the most common symptoms. was the commonest pathogen isolated from sputum samples. Spirometry showed obstructive pattern in majority of patients and cystic bronchiectasis being most common radiological pattern.
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