三叉神经痛药物致药物性口炎病例分析

Pavani Reddy, Ganesh C
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引用次数: 0

摘要

我们的研究目的是描述和评估一名35岁的女性患者在使用卡马西平治疗三叉神经痛后出现的口腔溃疡,该患者有过去十年的高血压病史并正在服药。在过去的一个月里,患者也有左侧面部触电样疼痛的病史,并开了替格列托尔100mg(卡马西平),每日两次。服用这种药物后,病人出现了几处口腔溃疡。要求患者停止服用该药,并要求口服抗组胺药和全身加巴喷丁类固醇一个月。一周后,病人的损伤完全愈合。烧灼感伴味觉改变和吞咽困难是患者常见的主诉。张口受限且疼痛。皮肤试验(点刺试验)显示红色、丘疹或水疱反应。早期发现病变并及时停药是成功治疗的关键,而且这种药物可以用另一种疗效相同的药物代替。因此,在开处方时询问患者对任何药物或食物的过敏情况,可以最大限度地减少药物不良反应,并且患者应该被告知并熟悉患者过敏的情况。
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Case Study of Stomatitis Medicamentosa Due to Trigeminal Neuralgia Medication
Our study aim is to characterize and assess the case of Stomatitis medicamentosa in a patient who developed manyoral ulcers after using Carbamazepine for the treatment of Trigeminal Neuralgia of a 35-year-old female patient with a medicalhistory of hypertension for the past ten years and under medication. The patient also gave a history of electric shock-like painon the left side of the face for the past month and was prescribed Tegretol 100mg (Carbamazepine) twice daily. After taking thismedication, the patient suffered several mouth ulcers. The patient was asked to stop taking this medication and asked to takeoral antihistamines and systemic Gabapentin steroids for one month. After one week, the patient heals completely from thelesions. Burning sensation with altered taste sensation and difficulty while swallowing are common patient complaints. Mouthopening was restricted and painful. The skin test (prick test) is done, which shows red, papular, or vesicular reactions. Earlyidentification of the lesion and prompt withdrawal of the offending drug are key for successful management, and the drug can bereplaced with another drug of the same efficacy. Thus, adverse drug reactions can be minimised by asking the patient aboutallergy to any drug or food while writing a prescription, and the patient should be informed and familiarised with the drugpatient the patient is allergic.
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