Epidemiological, entomological and evolutionary aspects of confirmed yellow fever cases from 2021 to 2022 in CAR

Ten countries in the African region, including the Central African Republic (CAR), were in epidemics. The objective of this study was to describe the epidemiological, entomological and evolutionary aspects of the yellow fever epidemic in CAR. This is a retrospective study for descriptive purposes. The survey population consists of confirmed yellow fever cases from 2021 to 2022 in CAR. The data came from the basics of epidemiological surveillance, epidemiological and entomological investigations. The data was entered by word 2013 and analyzed by Excel 2013 and Epi Info 7. During the reporting period, 533 suspected cases of yellow fever were reported. Ten confirmed patients and 18 asymptomatic contacts (64%) were included in this study. The case fatality rate was 30%. The symptoms observed in the patients were jaundice (80%) and haemorrhages (10%). Farmers were affected in 61% of cases. The species Aedes aegypti and Aedes vittatus, known in yellow fever transmission, have been found among mosquitoes caught in epidemic districts. Yellow fever is still a public health problem in CAR. Its variable clinical form (symptomatic and asymptomatic) must attract the attention of epidemiological surveillance actors to double their vigilance. Key works: Yellow fever, investigation, confirmed case, outbreak, CAR.