The role of phytocomponents in the complex therapy of chronic non-calculous cholecystitis

Non-calculous cholecystitis is a form of cholecystitis caused by dysfunction or hypokinesis of the gallbladder. The polyetiology and multiplicity of the pathogenesis of this disease requires different approaches to its correction. In this situation, phytopreparations containing components of origin provide special attention in combination with the main therapy. Curcumin has a strong protective effect against cholestasis through farnesoid X receptors, resulting in a release of bile acid homeostasis and counteracting inflammatory inflammation and as a manifestation of cholestasis. Several studies show that curcumin requires a contraction of the gallbladder. Despite the presence of many useful properties, the widespread use of curcumin in medical practice was limited by its limited bioavailability. Forms with increased bioavailability have been synthesized, such as kavacarcumin. The use of artichoke leaf extract in gastroenterology is based on its strong antidyspeptic effect, mediated by choleretic activity. As study show, the choleretic effect of the artichoke was more pronounced than that of the reference drug. In the description, there is no direct effect of chamomile phytocomponents on the state of bile compatibility and the function of bile outflow, however, an indirect effect on its work is possible. The results make chamomile flower extract a good addition to therapy. Thus, due to the occurrence of synergistic components, the complex is found in individuals, in patients with chronic diseases of the biliary tract, with functional disorders, the period of treatment in long-term complex therapy, with the prevention of exacerbation and prolongation of remission, as well as in healthy individuals for the prevention of these diseases.