14岁青少年胰腺实性假乳头瘤合并黑黑症1例

IF 0.3 Q4 PEDIATRICS Journal of Pediatrics Review Pub Date : 2023-07-01 DOI:10.32598/jpr.11.3.1063.1
Fateme Fazeli, Emad Asgari Jafarabadi, Amir Hossein Zardast, Marjan Joodi, Ghodsiyeh Azarkar
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引用次数: 0

摘要

背景:婴儿和儿童胰腺肿瘤的发病率为每100万1.8例。儿童最常见的三种原发性胰腺肿瘤是胰腺母细胞瘤、胰腺实性假乳头状肿瘤和胰腺内分泌肿瘤。胰腺实性假乳头状肿瘤是一种低度恶性肿瘤。儿童实性假乳头状肿瘤表现为可触及的肿块(60%),其次是腹痛(33.3%)。虽然胰腺癌患者常发生十二指肠侵犯,但消化道大出血却很少发生。最有用的成像技术是CT扫描。手术切除是治疗实性假乳头状瘤的首选方法。病例介绍:一名14岁男性青少年因疲劳、头晕、发烧、呕吐和心动过速被送到我们的儿科急诊科。入院前5天患有黑肠病。给予晶体剂、泮托拉唑和填充红细胞以稳定患者。由于初步复苏措施稳定了患者,进行了胃十二指肠镜检查,在十二指肠第二部分发现了一个血管病变,尺寸为60×70 mm。腹部CT扫描经静脉和口服造影显示胰腺头部和胰腺头部胆囊之间有一个固体和囊性成分的肿块,大小为75×52 mm。病人接受了惠普尔手术。病理诊断为胰腺实性假乳头状瘤。结论:大多数儿童胰腺假乳头状肿瘤表现为可触及的肿块和腹痛,消化道出血是一种罕见的表现,在以前的病例报告中没有提到。
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Solid Pseudopapillary Tumor of Pancreas in a 14-year-old Adolescent Presenting With Melena: A Case Report
Background: The incidence of pancreatic neoplasms in infants and children is 1.8 cases per 1000000. Three of children’s most common primary pancreatic neoplasms are pancreatoblastoma, solid pseudopapillary neoplasm of the pancreas, and pancreatic endocrine neoplasms. Solid pseudopapillary neoplasm of the pancreas is a low-grade malignant tumor. Solid pseudopapillary neoplasm in children is presented with a palpable mass (60%), followed by abdominal pain (33.3%). Although duodenal invasion frequently occurs in patients with pancreatic cancer, massive gastrointestinal bleeding is seldom encountered. The most helpful imaging technique is the CT scan. Surgical resection is the treatment of choice for solid pseudopapillary neoplasms. Case Presentations: A 14 years old male adolescent was presented to our pediatric emergency department with fatigue, dizziness, fever, vomiting, and tachycardia. He had melena 5 days before admission. Crystalloids, pantoprazole, and packed red blood cells were administered to stabilize the patient. As the initial resuscitation measures stabilized the patient, endoscopic gastroduodenoscopy was performed, and a vascular lesion measuring 60×70 mm was noted in the second part of the duodenum. CT scan of the abdomen with intravenous and oral contrast showed a mass with solid and cystic components measuring 75×52 mm between the head of the pancreas and gallbladder origination from the head of the pancreas. The patient underwent Whipple surgery. The diagnosis of the pathologic evaluation was a solid pseudopapillary tumor of the pancreas. Conclusions: Most pediatric pseudopapillary tumors of the pancreas present with a palpable mass and abdominal pain, and gastrointestinal bleeding is a rare presentation not mentioned in previous case reports.
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