血清乳酸水平的全身性升高是否与头颈部重建手术中游离皮瓣的失效有关

IF 0.5 Q4 ANESTHESIOLOGY Ain-Shams Journal of Anesthesiology Pub Date : 2023-09-12 DOI:10.1186/s42077-023-00370-2
Sapna Annaji Nikhar, Rajasekhar Metta, Raja Nimmagadda, R. Gopinath
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摘要

摘要背景头颈部重建手术需要自由组织移植,但有时手术失败。由于大部分皮瓣衰竭发生在24小时内,局部乳酸水平或葡萄糖乳酸比值的升高是组织缺血和进一步恢复的明确指标。问题是关于皮瓣衰竭时乳酸水平的全身性上升。因此,我们的目的是用全身乳酸水平来指示游离皮瓣失败。目的探讨头颈部重建手术中全身血清乳酸水平升高与游离皮瓣失效的关系。这一系列的病例是有针对性的接受游离腓骨移植,选择性地进行头部和重建手术,由同一位外科医生操作。并记录出血量、输血需求及微跨度的使用情况。监测动脉血气值,主要是乳酸和生命体征。结果15例患者中,只有2例(13.3%)患者进行了皮瓣再探查(F组),12例(80%)患者为ASA i级患者。两组24 h内乳酸、pH、血糖、碱基缺损、血红蛋白及生命体征比较,两组差异无统计学意义。所有病例在手术开始后的最初几个小时内均出现乳酸升高,但在皮瓣重新探查的几个小时内未观察到乳酸升高。结论乳酸水平的全身性升高与皮瓣再探查或皮瓣衰竭之间的关系尚不能确定,但持续的酸中毒会影响预后。我们需要保持警惕,需要采取个性化的管理方法。
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Does the systemic rise in serum lactate levels correlate to free flap failure in head and neck reconstructive surgeries—series of cases
Abstract Background Head and neck reconstructive surgeries needs free tissue transfer but it fails sometimes. As most of the flap failure occurs in first 24 h. Local rise in lactate level or glucose lactate ratio provides clear indicator of tissue ischemia and further recovery. The question is about systemic rise in lactate levels with failing flap. Hence, we aimed to use systemic lactate levels to indicate free flap failure. To correlate the systemic rise in serum lactate levels to free flap failure in head and neck reconstructive surgeries. The series of cases were targeted undergoing free fibular graft, posted electively for head and reconstructive surgery operated by same surgeon. Record of blood loss, need of blood transfusion and use of microspan was also done. Monitoring of arterial blood gas values mainly lactate and vitals were done. Results Out of 15 patients studied, only 2(13.3%) patients had flap re-exploration (group F). Twelve (80%) patients were of ASA class I. Lactate, pH, blood sugars, base deficits and hemoglobin and vitals studied over 24 h in two groups had no statistically significant difference in the two groups. Lactate rise was noted in all cases for first few hours after starting surgery but elevated values were not observed during hours of flap re-exploration. Conclusions We could not establish relation between systemic rise in lactate levels and flap re-exploration or flap failure but continuous acidosis can impact outcome. We need to be vigilant and need to have individualized approach for management.
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