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{"title":"mFOLFIRINOX治疗胰腺腺泡细胞癌术后多发肝及腹膜转移的成功案例- 1例报告","authors":"Gento SASAKI, Kenji OMURA, Kohei MISHIMA, Masahiko SUGITANI, Tomohisa OKOCHI, Yoshiki FUJIYAMA","doi":"10.3919/jjsa.84.479","DOIUrl":null,"url":null,"abstract":"65歳，女性．心窩部痛と背部痛を主訴に当院消化器内科を受診し，精査で膵頭部に5.4×3.3cm大の嚢胞性病変を認め，膵管内乳頭粘液性腺癌（cT2N1M0 cStage IIB）の疑いで亜全胃温存膵頭十二指腸切除術を施行した．R0切除が得られたが，術後3カ月で多発肝転移を認めた．GEM+nab-PTX療法を6コース行ったが，腹膜転移をきたした．追加で施行した免疫染色により膵腺房細胞癌（pT3N1M0 pStage IIB）との診断となった．GEM+nab-PTX療法が奏効しなかったことからmFOLFIRINOX療法に変更し，6コース行った時点で多発肝転移の消失と腹膜転移の著明な縮小を認め，PRを得た．現在，術後14カ月生存中である．","PeriodicalId":19305,"journal":{"name":"Nihon Rinsho Geka Gakkai Zasshi (journal of Japan Surgical Association)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Successful Use of mFOLFIRINOX Therapy for Postoperative Multiple Liver and Peritoneal Metastases of Pancreatic Acinic Cell Carcinoma—A Case Report—\",\"authors\":\"Gento SASAKI, Kenji OMURA, Kohei MISHIMA, Masahiko SUGITANI, Tomohisa OKOCHI, Yoshiki FUJIYAMA\",\"doi\":\"10.3919/jjsa.84.479\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"65歳，女性．心窩部痛と背部痛を主訴に当院消化器内科を受診し，精査で膵頭部に5.4×3.3cm大の嚢胞性病変を認め，膵管内乳頭粘液性腺癌（cT2N1M0 cStage IIB）の疑いで亜全胃温存膵頭十二指腸切除術を施行した．R0切除が得られたが，術後3カ月で多発肝転移を認めた．GEM+nab-PTX療法を6コース行ったが，腹膜転移をきたした．追加で施行した免疫染色により膵腺房細胞癌（pT3N1M0 pStage IIB）との診断となった．GEM+nab-PTX療法が奏効しなかったことからmFOLFIRINOX療法に変更し，6コース行った時点で多発肝転移の消失と腹膜転移の著明な縮小を認め，PRを得た．現在，術後14カ月生存中である．\",\"PeriodicalId\":19305,\"journal\":{\"name\":\"Nihon Rinsho Geka Gakkai Zasshi (journal of Japan Surgical Association)\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nihon Rinsho Geka Gakkai Zasshi (journal of Japan Surgical Association)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3919/jjsa.84.479\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nihon Rinsho Geka Gakkai Zasshi (journal of Japan Surgical Association)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3919/jjsa.84.479","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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