使用Beers标准评估老年处方的综合用药和适宜性:一项三级护理医院的前瞻性观察研究

Krishnananda Kamath K, Sanjay Kumar HK, Ramakrishna Shabaraya A
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摘要

摘要:背景:近年来我国老年人口不断增加。就药物处方而言,这一人群被认为是一个特殊的风险群体,因为多种用药和与年龄相关的生理变化使他们更容易受到药物的有害影响。有不同的工具来评估处方的适当性在老年病学。比尔斯的标准是最常用的工具之一,以确定一个老年患者的处方适当性。该研究的主要目的是利用比尔斯标准评估三级护理医院老年患者的多药和处方的适当性。材料和方法:对老年患者(>65岁)进行前瞻性观察性研究,为期7个月,采用有效的数据收集表。处方和住院病例档案用于收集人口统计信息和所开药物的具体情况。结果:2例患者完全残疾,GFI评分为4分,完全卧床。74%的处方中存在多药。50例(33.3%)患者根据Beers标准至少服用了一种可能不适当的药物。目前的研究没有发现虚弱和已确定的pim之间有任何关联,但是在处方药物数量和已确定的pim的合并症之间存在正相关。结论:多种用药和潜在不适当用药在老年人群中非常普遍,具有重要的医疗效果。在给老年人开处方之前,应该考虑到各种标准,比如被称为黄金标准的比尔斯标准。关键词:比尔斯标准,老年病学,虚弱,综合用药。
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Assessment of Polypharmacy and Appropriateness of Geriatric Prescription Using Beers Criteria: A Prospective Observational Study at a Tertiary Care Hospital
Abstract: Background: The elderly population has constantly been rising over the past few years. As far as drug prescribing is concerned, this population is considered to be a particular risk group as polypharmacy and age-related physiological changes make them more vulnerable to the harmful effects of drugs. There are different tools to assess the appropriateness of prescription in geriatrics. Beers criteria are one of the most used tools for determining an elderly patient's prescription appropriateness. The study's main objective was to assess polypharmacy and appropriateness of prescription among geriatric patients of a tertiary care hospital using Beers criteria. Materials and Methods: A prospective observational study was carried out on geriatric patients (>65 years) of either gender for a period of 7 months with a validated data collection form. Prescriptions and in-patient case files were used to gather demographic information and specifics about the medications prescribed. Results: Two participants were completely disabled, i.e., GFI score 4, totally confined to bed. Polypharmacy was present in 74% of prescriptions. 50 (33.3%) Patients were on at least one potentially inappropriate medication as per Beers criteria. The current study did not see any association between frailty and PIMs identified, but there was a positive correlation seen between the number of drugs prescribed and co-morbidities with identified PIMs. Conclusion: Polypharmacy and Potentially Inappropriate medications are highly prevalent in the geriatric population, which has a significant healthcare outcome. Various criteria like Beers Criteria which is referred to as the golden standard, should be taken into account before prescribing drugs to the elderly population. Keywords: Beers criteria, Geriatrics, Frailty, Polypharmacy.
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